eIF4EBP3 was downregulated by methylation and acted as a tumor suppressor by targeting eIF4E/ β-catenin in gastric cancer

ConclusionThese results suggest that eIF4EBP3 is a novel TSG methylated in gastric cancer that may play important roles in GC development and liver metastasis and indicate eIF4EBP3 as a potential metastasis and survival biomarker for GC.
Source: Gastric Cancer - Category: Gastroenterology Source Type: research