Cold Renal Perfusion During Simulation of Juxtarenal Aortic Aneurysm Repair Reduces Systemic Oxidative Stress and Sigmoid Damage in Rats

Juxtarenal aortic surgery induces renal ischaemia reperfusion, which contributes to systemic inflammatory tissue injury and remote organ damage. Renal cooling during suprarenal cross clamping has been shown to reduce renal damage. It is hypothesised that renal cooling during suprarenal cross clamping also has systemic effects and could decrease damage to other organs, like the sigmoid colon.

Source: Journal of Vascular Surgery - December 18, 2019 Category: Surgery Authors: T.G. van Schaik, V. Jongkind, R.J. Lindhout, J. van der Reijden, W. Wisselink, P.A.M. van Leeuwen, R.J.P. Musters, K.K. Yeung Source Type: research