Outcomes of Descemet-Stripping Automated Endothelial Keratoplasty in Congenital Hereditary Endothelial Dystrophy

Conclusion: Descemet-stripping automated endothelial keratoplasty is a safe and successful procedure in children with an acceptable graft survival in a mid-term follow-up period. A marked hyperopic shift could occur after DSAEK in children with CHED.
Source: Eye and Contact Lens: Science and Clinical Practice - Category: Opthalmology Tags: Article Source Type: research

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Descemet membrane detachment (DMD) is a potential vision-threatening complication that occurs most commonly after cataract surgery. DMD has also been reported to occur in various other surgeries like keratoplasty, iridectomy, vitrectomy, trabeculectomy, holmium laser sclerostomy, alkali burn, and viscocanalostomy. Major risk factors include advanced age, preexisting endothelial diseases like Fuchs dystrophy or abnormality in the Descemet membrane and stromal interface, hard cataract, prolonged surgical time, ragged clear corneal incisions, and inadvertent trauma with blunt instruments or phacoemulsification probe.
Source: Survey of Ophthalmology - Category: Opthalmology Authors: Tags: Major review Source Type: research
Conclusions: DM suturing can reattach DM, especially in moderate to severe, recurrent DMD with fewer postoperative complications and thereby reduce the need for corneal transplantation.
Source: Cornea - Category: Opthalmology Tags: Clinical Science Source Type: research
To identify preoperative corneal tomographic features that predict progression to endothelial keratoplasty (EK) following cataract surgery in Fuchs endothelial corneal dystrophy (FECD) and establish a regression model to identify high-risk patients.
Source: American Journal of Ophthalmology - Category: Opthalmology Authors: Tags: Original Article Source Type: research
To identify preoperative corneal tomographic features that predict progression to Endothelial Keratoplasty (EK) following cataract surgery in Fuchs Endothelial Corneal Dystrophy (FECD) and establish a regression model to identify high-risk patients.
Source: American Journal of Ophthalmology - Category: Opthalmology Authors: Tags: Original Articles Source Type: research
Conclusions: DWEK induces an increased central posterior float localized to the site of Descemet membrane stripping, confirming the need for centralized stripping. Irregular astigmatism can occur after DWEK but is typically minimal and occurs more commonly in the setting of preoperative irregular astigmatism. DWEK induces about a 0.5 D hyperopic shift, which should be considered when determining intraocular lens power with simultaneous surgery.
Source: Cornea - Category: Opthalmology Tags: Clinical Science Source Type: research
This study prospectively evaluated the use of ripasudil in patients undergoing DSO for FD. Methods: Enrolled patients underwent DSO with or without cataract surgery, performed by 1 surgeon. On the first postoperative day, patients were assigned to topical ripasudil 0.4% (Glanatec) 4 times a day for 2 months or no ripasudil and followed up monthly for the first 6 months and then at 9 and 12 months after surgery. Endothelial cell density (ECD) and pachymetry were evaluated at each postoperative visit. Results: Eighteen patients were enrolled, including 8 women and 1 man in each group. Overall, patients who underwent DS...
Source: Cornea - Category: Opthalmology Tags: Clinical Science Source Type: research
Conclusions: Our study demonstrates no difference in DMEK outcome with regard to rebubble rate whether the procedure is performed in combination with cataract surgery, in pseudophakia, or in phakia. Furthermore, donor age, initial graft cell count, and graft preparation technique did not impact rebubble rate. BCVA was also not affected by the need for rebubbling.
Source: Cornea - Category: Opthalmology Tags: Clinical Science Source Type: research
Conclusions: Increased IOP at 2 hours is common after DMEK, but does not seem to influence early endothelial cell survival. One-month ECD was influenced by donor counts and combined cataract surgery.
Source: Cornea - Category: Opthalmology Tags: Clinical Science Source Type: research
In this study, postoperative intraocular pressure (IOP) is investigated in this regard. Methods: In total, 1047 DMEK procedures in patients with Fuchs endothelial dystrophy or bullous keratopathy were reviewed. All rebubbling procedures were recorded as well as postoperative IOP values (first measure 2 hours postoperatively and highest and lowest value within 3 days after surgery), donor factors (donor age, organ culture time, and endothelial cell count), and whether DMEK surgery had been combined with cataract surgery (triple-DMEK). Incidence rates were estimated with the Kaplan–Meier method. Cox regression was u...
Source: Cornea - Category: Opthalmology Tags: Clinical Science Source Type: research
Conclusions: Compared with DMEK, NT-DSAEK provides comparable visual outcomes and complications rates.
Source: Cornea - Category: Opthalmology Tags: Clinical Science Source Type: research
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