Benchmarking machine learning models for late-onset alzheimer ’s disease prediction from genomic data
Late-Onset Alzheimer ’s Disease (LOAD) is a leading form of dementia. There is no effective cure for LOAD, leaving the treatment efforts to depend on preventive cognitive therapies, which stand to benefit from ...
DiscussionAs detailed above, the “elements” in both a classical and a contemporary sense have effects on our mental health and are potentially modifiable aspects that can be harnessed as therapeutic interventions. The most robust interventional evidence currently available shows tentative support for several use of the elements via horticultural and nature-exposure therapy, green exercise/physical activity, sauna and heat therapy, balneotherapy, and breathing exercises. It should be noted that, in many cases, these interventions were not studied in definitive diagnosed psychiatric disorders and thus it is prema...
This study had a large sample size and obtained positive findings in both patients’ subjective ratings and in inflammatory marker levels. It demonstrates the benefits of adding Tai Chi to an antidepressant regimen but does not examine the specific effect of Tai Chi on depression.Field et al. (16) investigated the effects of combined Tai Chi/yoga in 92 prenatally depressed pregnant women. They found that women practicing Tai Chi/yoga (20 min per week for 12 weeks) had lower depression, anxiety, and sleep disturbance scores compared to a waitlist control group (Table 1). This study had a large sample size and provided ...
Conditions: Alzheimer Disease; Mild Cognitive Impairment; Dementia; Cognition Disorders in Old Age; Cognitive Decline; Cognitive Deterioration Intervention: Device: Combination of 40Hz light and cognitive therapy (ALZLIFE) Sponsor: Alzheimer's Light LLC Recruiting
Patients with Lewy body dementia typically suffer from symptoms of parkinsonism, visual hallucinations and fluctuating cognition with a pronounced attentional impairment. However, the underlying network dysfunctions of the latter are unclear, which obstructs applying targeted cognitive therapies. Therefore we aimed to study network interactions during attentional processing in Lewy body dementia and compare them with Alzheimer ”s disease and healthy controls.
ConclusionThe caregivers had gained increased awareness of coping strategies in everyday life six to twelve months after the intervention. Caregivers who experienced fewer neuropsychiatric symptoms in their spouses with dementia benefitted most from the intervention.This article is protected by copyright. All rights reserved.
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CONCLUSION: this strategy can be considered a light technology of nursing care for older people with dementia. When providing this care with the support of a nurse, caregivers re feel less anxious and understand the disease better. PMID: 26312524 [PubMed - as supplied by publisher]