Picroside II protects against cholestatic liver injury possibly through activation of farnesoid X receptor

ConclusionOur findings demonstrate that picroside II exerts protective effect on ANIT-induced cholestasis possibly through FXR activation that regulates the transporters and enzymes involved in bile acid homeostasis. Picroside II might be an effective approach for the prevention and treatment of cholestatic liver diseases.Graphical abstract
Source: Phytomedicine - Category: Drugs & Pharmacology Source Type: research