Covariation between spontaneous neural activity in the insula and affective temperaments is related to sleep disturbance in individuals with major depressive disorder.

CONCLUSIONS: The resting-state spontaneous activity of the anterior insula and affective temperaments collaboratively contribute to sleep disturbances in medication-free MDD patients. The approach used in this study provides a practical way to explore the relationship of multivariate measures in investigating the etiology of mental disorders. PMID: 31839025 [PubMed - as supplied by publisher]

https://www.ncbi.nlm.nih.gov/pubmed/31839025?dopt=Abstract

Source: Psychological Medicine - December 15, 2019 Category: Psychiatry Authors: Wu H, Zheng Y, Zhan Q, Dong J, Peng H, Zhai J, Zhao J, She S, Wu C Tags: Psychol Med Source Type: research