Ethnopharmacological Potentials of Warburgia ugandensis on Antimicrobial Activities
AbstractWarburgia ugandensis (W. ugandensis) is known by various names, including the East African greenheart, pepper bark tree, and Ugandan greenheart, and has a rich history of extensive use in the treatment of a host of human diseases in many African countries. This review is based on the botany and ethnopharmacological potentials ofW. ugandensis for the treatment of pneumonia, asthma, malaria, candidiasis, skin infections, human immunodeficiency virus opportunistic infections, diarrhea, and measles given the common use in the management of these diseases. Extracts fromW. ugandensis have strong antimicrobial activities against a broad spectrum of pathogens mainly because of the presence of abundant terpenoids, drimane, and coloratane type sesquditerpenoids amongst which are ugandensial, warburganal, mukaadial, and other secondary metabolites, such as tannins, flavonoids, saponins, steroids, and mannitol. This group of compounds gives the plant a high therapeutic value. Based on the review, there is a need for identification and isolation of the highly therapeutic phytochemical constituents and a drive for more preclinical and clinical trials to validate the safety and efficacy of the extracts. This gives basis for the potential development of new therapeutic drugs from the plant.
CONCLUSION: Majority of the viewers used mobile phones, and mobile phones and tablets had significantly longer average view durations as compared to computer/TV. YouTube and wireless devices may have potential as internet based psychiatric emergency outreach platform. This study calls for further research to explore the effectiveness of using social media and wireless devices for psychiatric emergency education prior to ED arrival, particularly in minority populations with cultural barriers to health care. PMID: 32086173 [PubMed - as supplied by publisher]
Communist party expected to reveal whether it will delay annual parliamentary session and South Korea reports new spike in casesWuhan, the centre of the coronavirus outbreak in China, has loosened lockdown measures and several provinces have lowered their emergency alert levels, as top officials sought to assure the public that the virus is being contained.On Monday, China ’s National Health Commission reportedits highest number of deaths in 11 days, with another 150 dead and 409 new cases, bringing the total number of confirmed cases of Covid-19 in China to 77,150.All but one of the fatalities and 11 of the new infe...
CONCLUSIONS: Our findings support the use of omalizumab in selected forms of EGPA, but caution in the tapering of corticosteroids is also recommended. Quality of evidence is limited, as the source of information was mainly case reports. Clinical trials are required in order to evaluate the role of omalizumab in EGPA and to ascertain the risk of asthmatic patients given omalizumab to develop EGPA. PMID: 32083537 [PubMed - as supplied by publisher]
Fears grew on Monday that the coronavirus outbreak in China will grow into a pandemic with disruptive and deadly consequences for countries around the world, after sharp rises in infections in South Korea, Italy and Iran.
International concern about the spread of coronavirus outside China grew on Sunday with sharp rises in infections in South Korea, Italy and Iran.
Publication date: Available online 22 February 2020Source: Microbiological ResearchAuthor(s): Jiakang Yin, Youfeng Yu, Ziliang Zhang, Lingling Chen, Lifang RuanAbstractThe soil microbiota interacts with plants closely and exerts strong influences on plant health and productivity. However, the relationship between the microbiota and the bacterial canker of tomato that is caused by Clavibacter michiganensis subsp. michiganensis (Cmm) is still unclear. In order to establish causal relationship between the microbiota and plant phenotypes, the microbial communities of 49 tomato samples (including 15 cultivars) with different ca...
ConclusionsIn this study, the majority of MRSE belonged to cluster II domain of CC2. The ST59-IV was a dominant clone among isolates recovered from hospital personnel. Determination of new MLST types confirmed the genetic diversity of these isolates. These observations highlight the need to review the infection control strategies to reduce the carriage of MRSE among hospital personnel.
Authorities in Italy announced that all Carnival events had been called off as the region tries to contain the outbreak. In China, more than 2,400 people have died from COVID-19, the disease caused by the coronavirus.