Effectiveness of glatiramer acetate in neutralizing antibody-positive patients previously treated with interferon-β.

Conclusion: While on GA, patients switched from IFNβ in the context of disease activity and no NAbs had the highest risk of future disease activity, while NAb positive patients without previous activity had the lowest. We did not find any average difference between NAb-positive patients switching in a context of disease activity and NAb-negative patients switched due to adverse events, although carefulness in the interpretation of this result is advised.
Source: Multiple Sclerosis and Related Disorders - Category: Neurology Source Type: research