Differential blockade by huperzine A and donepezil of sympathetic nicotinic acetylcholine receptor-mediated nitrergic neurogenic dilations in porcine basilar arteries.
In conclusion, huperzine A may exert less harmful effect over donepezil on maintaining brainstem circulation and on the nicotinic acetylcholine receptor-associated cognition deficits during treatment for Alzheimer's disease.
PMID: 31836535 [PubMed - as supplied by publisher]
Source: European Journal of Pharmacology - Category: Drugs & Pharmacology Authors: Shih CC, Chen PY, Chen MF, Lee TJF Tags: Eur J Pharmacol Source Type: research
More News: Alzheimer's | Brain | Calcium | Donepezil | Drugs & Pharmacology | Neurology | Neuroscience | Nicotine | Reflex Sympathetic Dystrophy | Science | Sodium