Teriparatide improves pain-related behavior and prevents bone loss in ovariectomized mice.

CONCLUSION: TPTD treatment prevented ovariectomy-induced bone loss and ovariectomy-induced mechanical hyperalgesia in hind limbs, and it suppressed CGRP and TRPV1 expressions in DRG neurons. These results suggest that TPTD is useful for the treatment of osteoporotic pain in postmenopausal women. PMID: 31833446 [PubMed - in process]

https://www.ncbi.nlm.nih.gov/pubmed/31833446?dopt=Abstract

Source: Journal of Orthopaedic Surgery - December 15, 2019 Category: Orthopaedics Authors: Kato S, Wakabayashi H, Nakagawa T, Miyamura G, Naito Y, Iino T, Sudo A Tags: J Orthop Surg (Hong Kong) Source Type: research