Nonspecific oral mucositis in a patient with Crohn's disease

ConclusionsThis case demonstrates the simultaneous presentation of multiple conditions. Oral biopsy revealed a solitary focus of granulomatous inflammation, indicative of orofacial granulomatosis. However, the biopsied lesion was also unusual in that inflammation extended into the epithelium, a relatively unusual feature for a granulomatous inflammatory disease and a pattern more commonly seen in vesiculobullous eruptions. Because this patient's CD was well controlled, it is difficult to believe that these oral lesions were associated with CD activity. One reasonable assumption is that the long-time treatment of the patient's CD with infliximab might have hindered histologic and immunologic identification to establish a more definitive diagnosis.
Source: Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology - Category: ENT & OMF Source Type: research

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