Comparative study on the efficacy of high-dose oral ascorbic acid with/without zinc in reducing the severity of oral mucositis during cancer chemoradiation

ConclusionsZinc with or without vitamin C demonstrated significant decrease in the severity of oral mucositis compared with vitamin C alone. Pain decreased with vitamin C supplementation compared with controls. Vitamin C use reduced pain perception, and zinc reduced the mucositis scores. A combination of zinc and vitamin C showed benefits, including pain reduction, mucositis reduction, and taste preservation.
Source: Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology - Category: ENT & OMF Source Type: research