22 q11.2 deletion sydrome and alteration in oral cavity: clinical case report

The 22 q11.2 deletion syndrome, also known as DiGeorge syndrome, is the subject of the loss of a submicroscopic segment of DNA in the 22 q11.2 region. It presents a great variability of clinical characteristics in affected individuals. Among the clinical manifestations are fissure of the palate, nasal speech, cardiovascular problems, and dysmorphic facial features. This case report describes a 15-year-old girl, clinically diagnosed as having DiGeorge syndrome, who attended a dental service for patients with special needs presenting with malocclusion, difficulty in chewing, and suspected heart disease.
Source: Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontics - Category: ENT & OMF Authors: Source Type: research