Expression of cancer stem cells surface markers in tongue squamous cell carcinoma cell lines

Cancer stem cells (CSCs) comprise subpopulation of tumor cells associated with cancer initiation, progression, and treatment failures found in several malignancies, including oral squamous cells carcinoma (OSCC). Currently, among the methods employed for detection and isolation of CSCs the most used is flow cytometry immunophenotyping. The expression of surface markers for CSCs in SCC-9 cells, derived from tongue OSCC, has not been described in the literature.Objective: To identify and compare the expression of cell surface markers associate to CSCs in the SCC9 ZsGreen and its metastatic derivative SCC9 ZsGreen LN1 cells.
Source: Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontics - Category: ENT & OMF Authors: Source Type: research