Demyelination Initiated by Oligodendrocyte Apoptosis through Enhancing Endoplasmic Reticulum-Mitochondria Interactions and Id2 Expression after Compressed Spinal Cord Injury in Rats.

CONCLUSION: Demyelination occurred after CSCI and might be partly caused by oligodendrocyte apoptosis, which was positively correlated with ER-mitochondria interactions and enhanced Id2 expression after CSCI in rats. PMID: 23937638 [PubMed - as supplied by publisher]

http://www.ncbi.nlm.nih.gov/pubmed/23937638?dopt=Abstract

Source: CNS Neuroscience and Therapeutics - August 13, 2013 Category: Neuroscience Authors: Huang SQ, Tang CL, Sun SQ, Yang C, Xu J, Wang KJ, Lu WT, Huang J, Zhuo F, Qiu GP, Wu XY, Qi W Tags: CNS Neurosci Ther Source Type: research