Clinicopathologic Features of the Ureteral Neuroendocrine Tumors

ConclusionUreteral neuroendocrine tumors are extremely rare. Neuroendocrine markers (CD56, CgA, Syn) and epithelial markers (CKpan, CK7) are usually helpful. Grimelius special staining and electron microscopy observation can help to make a final diagnosis. Radical surgery together with postoperative adjuvant chemotherapy can improve the survival of patients. Vimentin may play a role in predicting the prognosis.
Source: Pathology Research and Practice - Category: Pathology Source Type: research

Related Links:

Conclusion T4 stage patients had worse survival in N2 group. To get a more precisely stratification, skip metastasis and number of involved lymph node stations should be considered in future N stage classification. 
 DOI: 10.3779/j.issn.1009-3419.2020.01.03
Source: Chinese Journal of Lung Cancer - Category: Cancer & Oncology Source Type: research
Conclusion Anlotinib effectively controlled the growth of NSCLC and improved TAO related symptoms. Anlotinib maybe normalize disordered growth of blood vessels through the VEGF signaling pathway, rather than simply inhibiting angiogenesis. 
 DOI: 10.3779/j.issn.1009-3419.2020.01.10
Source: Chinese Journal of Lung Cancer - Category: Cancer & Oncology Source Type: research
This study aims to synthesise and characterise magnetically responsive polymer colloids (MRPCs). Healthy tissue damage done by chemotherapy session could be minimised by MRPCs. For the colloidal formulation of MRPCs, the oil in water emulsion technique was employed with the aid of sonication and stirring. The organic phase of emulsion contained methotrexate (MTX) drug, Eudragit E100 and CoFe2O4 (synthesised by co-precipitation) in ethanol, and the aqueous phase contained tween 80 in deionised water. The emulsion was optimised by studying/adjusting two different parameters, i.e. the concentration of constituents and sonicat...
Source: IET Nanobiotechnology - Category: Nanotechnology Source Type: research
Publication date: Available online 15 January 2020Source: Neuroscience &Biobehavioral ReviewsAuthor(s): Anna Xu, Bart Larsen, Erica B. Baller, J. Cobb Scott, Vaishnavi Sharma, Azeez Adebimpe, Allan I. Basbaum, Robert H. Dworkin, Robert R. Edwards, Clifford J. Woolf, Simon B. Eickhoff, Claudia R. Eickhoff, Theodore D. SatterthwaiteAbstractCharacterizing a reliable, pain-related neural signature is critical for translational applications. Many prior fMRI studies have examined acute nociceptive pain-related brain activation in healthy participants. However, synthesizing these data to identify convergent patterns of activa...
Source: Neuroscience and Biobehavioral Reviews - Category: Neuroscience Source Type: research
.
Source: Journal of Agromedicine - Category: Environmental Health Authors: Source Type: research
We describe the adaptation of a model-based design for identifying the maximum tolerated dose combination that efficiently moves from the initial phase in an advanced disease population to the second phase in the target population. Operating characteristics demonstrate the ability of the method to accurately predict true maximum tolerated dose combinations in a high percentage of trials with reasonable sample sizes, while treating participants at and around desirable combinations. The proposed design is a practical, early-phase, adaptive method for use with drug combination dose finding in the presence of shifting patient ...
Source: Clinical Breast Cancer - Category: Cancer & Oncology Authors: Tags: Contemp Clin Trials Commun Source Type: research
Link N suppresses interleukin-1β-induced biological effects on human osteoarthritic cartilage. Eur Cell Mater. 2020 Jan 15;39:65-76 Authors: Alaqeel M, Grant MP, Epure LM, Salem O, AlShaer A, Huk OL, Bergeron SG, Zukor DJ, Kc R, Im HJ, Anbazhagan AN, Antoniou J, Mwale F Abstract Osteoarthritis (OA) is a disease of diarthrodial joints associated with extracellular matrix proteolytic degradation under inflammatory conditions, pain and disability. Currently, there is no therapy to prevent, reverse or modulate the disease course. The present study aimed at evaluating the regenerative potential of Link...
Source: European Cells and Materials - Category: Cytology Tags: Eur Cell Mater Source Type: research
Publication date: Available online 15 January 2020Source: Preventive MedicineAuthor(s): Kathleen Gali, Ruth Narode, Kelly C. Young-Wolff, Mark L. Rubinstein, Geoffrey Rutledge, Judith J. ProchaskaAbstractCannabis has been legalized, decriminalized, or medicalized in over half the U.S. states. With restrictions on cannabis research, accepted standards to guide clinical practice are lacking. Analyzing online communications through a digital health platform, we characterized patient questions about cannabis use and provider responses. Coded for content were 4579 questions posted anonymously online between March 2011 through J...
Source: Preventive Medicine - Category: International Medicine & Public Health Source Type: research
Want to ask people's opinion on this. Has been a follower on this forum and have found the input and discussion valuable Recently I have a few patients came to me, some by referral, but they don't have insurance, they want to pay cash for their visits but only want me to manage their opioid. Sometime I just don't know what to do with these patients, if I recommend procedures, it's probably too costly and they won't be able to afford or no interest in pursuing. I just don't like the optic of... Cash pay for narcotics
Source: Student Doctor Network - Category: Universities & Medical Training Authors: Tags: Pain Medicine Source Type: forums
ConclusionPathological fracture in young adult should always be properly investigated. A high index of suspicion is necessary to diagnose unusual presentation of Primary Hyperparathyrodism.
Source: International Journal of Surgery Case Reports - Category: Surgery Source Type: research
More News: Brain | Cancer & Oncology | Carcinoid Tumor | Carcinoma | Chemotherapy | Epithelial Cancer | Hydronephrosis | Neurology | Neurosurgery | Pain | Pathology | Ureter and Renal Pelvis Cancer