Bio-based polymer nanofiber with siliceous sponge spicules prepared by electrospinning: Preparation, characterisation, and functionalisation

In this study, SS attached to plant bodies were subjected to acid and heat treatments, followed by grinding, to obtain 10–40-nm siliceous sponge spicules (SSS). SSS and polylactic acid (PLA) were then combined to create 50–450-nm PLA/SSS composite nanofibers. The morphology and bioactivity of the electrospun PLA/SSS nanofibers were examined; the tensile, thermal, and water-resistant properties of the fibers were also evaluated. Our results showed a dramatic enhancement in the thermal and tensile properties of PLA with increasing SSS content; specifically, a 3 wt% increase in SSS content resulted in a 47 °C increase in the initial decomposition temperature and a 73.3-MPa increase in Young's modulus. The water resistance of PLA/SSS increased with SSS content, as indicated by the increase in the water contact angle compared with PLA nanofibers. PLA/SSS nanofibers also exhibited slightly enhanced human foreskin fibroblast cell proliferation, good cytocompatibility, and an antibacterial effect. The enhanced antibacterial and biodegradable properties of PLA/SSS are expected to be useful in biomedical material applications.Graphical abstract
Source: Materials Science and Engineering: C - Category: Materials Science Source Type: research

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Source: Nano Energy - Category: Nanotechnology Source Type: research
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Source: Cell - Category: Cytology Source Type: research
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Source: BPS RESEARCH DIGEST - Category: Psychiatry & Psychology Authors: Tags: Weekly links Source Type: blogs
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Source: International Journal for Parasitology: Parasites and Wildlife - Category: Parasitology Source Type: research
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Source: Molecular and Biochemical Parasitology - Category: Parasitology Source Type: research
Contributors : Sarah Forrester ; Amy Goundry ; Bruna Torres Dias ; Thyago Leal Calvo ; Milton Os ório Moraes ; Paul M Kaye ; Jeremy C Mottram ; Ana C de Araújo LimaSeries Type : Expression profiling by high throughput sequencingOrganism : Leishmania donovani ; Leishmania infantum ; Mus musculusFIve 6/8 week old female BALB/c mice were infected with the LV9 L. donovani strain,five mice were infected with the L. infantum NCL strain, five were uninfected, and spleen and liver were taken from mice at day 36 post infection. These tissues were then used to prepare for RNAseq
Source: GEO: Gene Expression Omnibus - Category: Genetics & Stem Cells Tags: Expression profiling by high throughput sequencing Leishmania donovani Leishmania infantum Mus musculus Source Type: research
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Source: Parasites and Vectors - Category: Microbiology Authors: Tags: Research Source Type: research
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Source: Journal of Biological Chemistry - Category: Chemistry Authors: Tags: ASBMB Award Articles Source Type: research
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