Heart Rate Variability as an Indicator of Autonomic Nervous System Disturbance in Tetanus.

Heart Rate Variability as an Indicator of Autonomic Nervous System Disturbance in Tetanus. Am J Trop Med Hyg. 2019 Dec 16;: Authors: Hai Duong HT, Abebe Tadesse G, Nhat PTH, Hao NV, Prince J, Duong TD, Kien TT, Nhat LTH, Van Tan L, Pugh C, Loan HT, Van Vinh Chau N, Minh YL, Zhu T, Clifton D, Thwaites L Abstract Autonomic nervous system dysfunction (ANSD) is a significant cause of mortality in tetanus. Currently, diagnosis relies on nonspecific clinical signs. Heart rate variability (HRV) may indicate underlying autonomic nervous system activity and represents a potentially valuable noninvasive tool for ANSD diagnosis in tetanus. HRV was measured from three 5-minute electrocardiogram recordings during a 24-hour period in a cohort of patients with severe tetanus, all receiving mechanical ventilation. HRV measurements from all subjects-five with ANSD (Ablett Grade 4) and four patients without ANSD (Ablett Grade 3)-showed HRV was lower than reported ranges for healthy individuals. Comparing different severities of tetanus, raw data for both time and frequency measurements of HRV were reduced in those with ANSD compared with those without. Differences were statistically significant in all except root mean square SD, indicating HRV may be a valuable tool in ANSD diagnosis. PMID: 31833471 [PubMed - as supplied by publisher]
Source: The American Journal of Tropical Medicine and Hygiene - Category: Tropical Medicine Authors: Tags: Am J Trop Med Hyg Source Type: research

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ConclusionsReceiving the birth dose is positively associated with up-to-date status later in childhood, highlighting the importance of starting vaccination early. The association is insensitive to confounding by factors observed in National Immunization Survey-Child, but investigation of unobserved factors such as vaccine hesitancy could provide critical information to guide intervention strategy.
Source: American Journal of Preventive Medicine - Category: International Medicine & Public Health Source Type: research
Conclusions: Our findings will assist health care professionals and policy makers in preparing targeted information campaigns to address questions and counteract vaccine hesitancy.
Source: The Pediatric Infectious Disease Journal - Category: Infectious Diseases Tags: Vaccine Reports Source Type: research
Abstract A 7-year-old unimmunized boy developed cephalic tetanus following chronic suppurative otitis media. We wish to emphasize that possibility of cephalic tetanus should be considered in an unimmunized child presenting with ptosis. PMID: 31937706 [PubMed - in process]
Source: Indian Pediatrics - Category: Pediatrics Authors: Tags: Indian Pediatr Source Type: research
The rise of vaccine-preventable illnesses, such as measles and hepatitis, in the United States and around the globe has been alarming in recent years. For women — especially those hoping to become pregnant, as well as women who are pregnant or have recently had a baby — vaccines can be a worrisome topic. There are many misconceptions about vaccine safety in and around pregnancy that can lead to confusion and unnecessary fear of a lifesaving medical tool. As a practicing ob/gyn, I often discuss vaccines with my patients and help them sort out fears versus facts. Which vaccines should you consider before concepti...
Source: Harvard Health Blog - Category: Consumer Health News Authors: Tags: Health Parenting Pregnancy Vaccines Women's Health Source Type: blogs
(Natural News) A new peer-reviewed scientific paper published in the journal Tropical Diseases, Travel Medicine and Vaccines has found that the DTaP vaccine for diphtheria, tetanus, and pertussis (whooping cough) is causing children who receive it to become more prone to contracting whooping cough later on in life. According to the study, children who receive...
Source: NaturalNews.com - Category: Consumer Health News Source Type: news
Conclusion: This review article provides an overview on the rationale and main mechanism of the maternal vaccination strategy and gives a summary about the current and possible future recommendations for maternal vaccination.What is Known:•Maternal vaccination has a far-reaching potential in the protection of both women and offspring.• Currently, tetanus, pertussis and influenza vaccination during pregnancy is recommended in some countries. Several new vaccines specifically designed for use in pregnancy are currently under development.What is New:•Review providing a timely overview of the rationale and main ...
Source: European Journal of Pediatrics - Category: Pediatrics Source Type: research
Publication date: Available online 2 January 2020Source: Veterinary MicrobiologyAuthor(s): John Baird, Birthe Tegtmeyer, Luis Arroyo, Alexander Stang, Yannick Brüggemann, Murray Hazlett, Eike SteinmannAbstractTheiler’s disease was confirmed within a group horses located on a farm in southwestern Ontario during the summer and autumn of 2005. Five sudden deaths occurred between 3 July and 21 August, 2005, none of which were necropsied, however two of the horses showed clinical signs compatible with hepatic encephalopathy prior to death. No horse on the farm had received a biologic product of equine blood origin in...
Source: Veterinary Microbiology - Category: Veterinary Research Source Type: research
William F. Gilly, Corbin Renken, Joshua Rosenthal, and William M. Kier An important aspect of the performance of many fast muscle fiber types is rapid excitation. Previous research on the cross-striated muscle fibers responsible for the rapid tentacle strike in squid has revealed the specializations responsible for high shortening velocity, but little is known about excitation of these fibers. Conventional whole-cell patch recordings were made from tentacle fibers and the slower obliquely striated muscle fibers of the arms. The fast-contracting tentacle fibers show an approximately tenfold greater sodium conductance than t...
Source: Journal of Experimental Biology - Category: Biology Authors: Tags: RESEARCH ARTICLE Source Type: research
Despite recommendations from the CDC, Advisory Committee on Immunization Practice and ACOG, tetanus, diphtheria, and acellular pertussis (Tdap) vaccination rates during pregnancy remain inadequate at 54.4% in 2017-2018. Vaccinating pregnant women confers passive immunity to infants, who experience significantly higher mortality from pertussis. However, women have commonly been vaccinated previously. We sought to examine this recommendation by assessing the cost-effectiveness of the Tdap vaccine in pregnant women for preventing pertussis infection in infants.
Source: American Journal of Obstetrics and Gynecology - Category: OBGYN Authors: Tags: Poster Session V Source Type: research
The primary aim was to determine the seroprevalence of anti-pertussis toxin antibodies (anti-PT IgG) among Thai pregnant women. The secondary aims were to evaluate antibodies response after tetanus toxoid, reduced diphtheria toxoid, and acellular pertussis (Tdap) vaccination between seronegative and seropositive mothers and to compare the different antibody titers at delivery among seropositive mothers who received Tdap to those who received tetanus-diphtheria vaccine (Td).
Source: American Journal of Obstetrics and Gynecology - Category: OBGYN Authors: Tags: Poster Session V Source Type: research
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