Vernoguinamide: A new ceramide and other compounds from the root of Vernonia guineensis Benth. and their chemophenetic significance
Publication date: February 2020Source: Biochemical Systematics and Ecology, Volume 88Author(s): Steven Collins N. Wouamba, Gervais Mouthé Happi, Bruno N. Lenta, Norbert Sewald, Siméon Fogué KouamAbstractThe chemical investigation of the roots of Vernonia guineensis Benth. (Asteraceae) resulted in the isolation of a new ceramide, named vernoguinamide (1), together with fifteen known compounds, including three anthraquinones, physion (2), erythroglaucin (3) and emodin (4), three triterpenoids, hop-17(21)-en-3β-yl acetate (5), lupeol (6) and betulinic acid (7), six steroids, vernoguinoside A (8), vernoguinoside (9), β-sitosterol 3-O-β-D-glucoside (10), stigmasterol 3-O-β-D-glucoside (11), stigmasterol (12) and β-sitosterol (13) and three fatty acid derivatives, tetracosanoic acid (14), tricosanic acid (15) and arachidic acid glycerol ester (16). The structure of the new compound as well as those of the known compounds were established by spectrometric analysis including HRESI-MS, 1D and 2D-NMR and by comparison with the previously reported data. Among these compounds, the anthraquinones 2–4 and the triterpene 5 were isolated for the first time from Vernonia genus and compounds 6, 7 and 14–16 were extracted for the first time from the species. The isolated compounds were tested for their antibacterial activity and 3, 8 and 9 were the most active compounds against the tested bacteria. Furthermore, the chemophenetic relation...
Authors: Khurram A, Abedi D, Abedi M PMID: 32497473 [PubMed - as supplied by publisher]
CONCLUSION: Use of VR facility tours as an alternative to in-person tours of affiliate training facilities during a residency interview day is a viable and innovative option that can save time and money and favorably impact the applicant's impression of the program. More research is necessary to assess whether VR tours can replace in-person tours at the main teaching site, however, while social distancing measures are in place, VR tours may become necessary for programs moving forward. ABBREVIATIONS: Med-Peds: Internal Medicine-Pediatrics; VR: Virtual Reality; AAMC: Association of American Medical Colleges; IRB: Instit...
Authors: Edigin E, Eseaton PO, Shaka H, Ojemolon PE, Asemota IR, Akuna E PMID: 32493181 [PubMed - in process]
Authors: Roberts V, Malone K, Moore P, Russell-Webster T, Caulfield R Abstract Our personal views about the challenges of continuing to deliver peer teaching during a pandemic. We are a group of 4th year medical students who are part of a student society which has delivered structured, highly formulaic peer-led teaching sessions for the past three years. During the COVID-19 pandemic, the reduced access to our normal clinical teaching highlighted the importance of peer-led teaching sessions. We wanted to continue with our peer-taught sessions but knew we would have to devise a new format to make our teaching accessi...
Publication date: Available online 5 June 2020Source: Journal of Microbiology, Immunology and InfectionAuthor(s): Chih-Cheng Lai, Cheng-Yi Wang, Wen-Chien Ko, Po-Ren Hsueh
Publication date: Available online 4 June 2020Source: Journal of Microbiology, Immunology and InfectionAuthor(s): Huei-Hsuan Chiu, Huai-Lei Juan, Po-Liang Lu, Ko Chang
Publication date: Available online 5 June 2020Source: Journal of Microbiological MethodsAuthor(s): Laura Villa, Aurora Torreblanca, Luis Otero, Francisco Carreño, Rainer Campo, María López-Escobar, Fernando Vazquez
Publication date: Available online 5 June 2020Source: Journal of Microbiological MethodsAuthor(s): Dennis L. Welker, Bailey L. Crowley, Justin B. Evans, Martin H. Welker, Jeff R. Broadbent, Robert F. Roberts, David A. Mills
Publication date: Available online 4 June 2020Source: Statistics &Probability LettersAuthor(s): Mohamed Marzougue
Publication date: December 2020Source: Physics of the Dark Universe, Volume 30Author(s): F.D. Villalba, P. Bargueño, A.F. Vargas, E. Contreras