HbA1c detection via high-sensitive boronate based surface plasmon resonance sensor

This study is shown that the pH value is an important parameter for binding and the signal received is increased as the concentration increases. Even at low concentrations like 10 μg/mL, signal can be received and it implies that more accurate measurement can be made at clinical concentration values which are higher. In artificial plasma studies, different sensograms are obtained for human serum albumin, immunoglobulin G, and hemoglobin molecules which all could bind to modified chip and the selectivity to the molecules are distinctively differentiated in comparison with HbA1c.
Source: Sensors and Actuators B: Chemical - Category: Chemistry Source Type: research