Shrinking leiomyomas by pharmacological autophagy other than surgical removal

Uterine myomas may have significant detrimental effects on menstruation and fertility. Regardless of their location within the uterus, they may reduce the chance of successful embryo implantation (clinical pregnancy) by 50% and increase the risk of pregnancy loss (1). While the negative impact of myomas on fertility seems clear, there is still no strong evidence regarding the influence of their removal on conception. Indeed, the latest Practice Bulletin from 2017 of the Practice Committee of the American Society for Reproductive Medicine (2) concludes that “myomectomy is generally not advised to improve pregnancy outcomes in asymptomatic infertile women with non-cavity‒distorting myomas” but states that it “may be reasonable in some circumstances.”
Source: Fertility and Sterility - Category: Reproduction Medicine Authors: Tags: Reflections Source Type: research