Comparison of Focal and Conventional Verteporfin Photodynamic Therapy for Chronic Central Serous Chorioretinopathy.

This study enrolled 52 eyes of 52 patients with chronic CSC who had received verteporfin PDT. The laser spot size of 26 eyes covering only the localized hyperfluorescent area in indocyanine green angiography was classified as focal PDT. The PDT spot size of the other 26 eyes covered the total area of retinal pigment epithelial detachment including the leaking point and was defined as conventional PDT. The central subfield thickness and subfoveal choroidal thickness were measured using Heidelberg Spectralis optical coherence tomography before PDT and at months 1, 3, 6, and 12 after PDT. RESULTS: The mean spot size of the PDT was 1,995 μm in the focal group and 2,995 μm in the conventional group. Central subfield thickness steadily decreased in both groups. The mean baseline subfoveal choroidal thickness for the two groups was 334.95 and 348.35 μm, respectively, with no significant difference (p = 0.602). Subfoveal choroidal thickness decreased significantly to 304.20 μm at 1 month, 284.85 μm at 3 months, 271.60 μm at 6 months, and 265.95 μm at 12 months in the focal group (p
Source: Korean Journal of Ophthalmology : KJO - Category: Opthalmology Tags: Korean J Ophthalmol Source Type: research

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AbstractBackground and purposeClinical outcome after endovascular thrombectomy in patients with acute ischemic stroke still varies significantly. Higher blood glucose levels (BGL) have been associated with worse clinical outcome, but the pathophysiological causes are not yet understood. We hypothesized that higher levels of BGL are associated with more pronounced ischemic brain edema and worse clinical outcome mediated by cerebral collateral circulation.Methods178 acute ischemic stroke patients who underwent mechanical thrombectomy were included. Early ischemic brain edema was determined using quantitative lesion water upt...
Source: Journal of Neurology - Category: Neurology Source Type: research
Retinal optical coherence tomography (OCT) and OCT angiography (OCTA) suffer from the degeneration of image quality due to speckle noise ...
Source: Optics Letters - Category: Physics Authors: Source Type: research
AbstractBackgroundThe randomized BASKET-SMALL 2 trial showed non-inferiority for treatment with drug-coated balloon (DCB) compared with drug-eluting stents (DES) in patients undergoing percutaneous coronary intervention (PCI) for de novo lesions in small coronary arteries regarding clinical endpoints at 1  year. In this predefined substudy, we investigated the angiographic findings in patients undergoing a clinically indicated follow-up angiography during the study phase.MethodsEight-hundred and eighty-three patients underwent PCI with either DES or DCB in a culprit vessel  
Source: Clinical Research in Cardiology - Category: Cardiology Source Type: research
Publication date: 2020Source: European Journal of Radiology Open, Volume 7Author(s): Hiroki Kamada, Hideki Ota, Yosuke Terui, Koichiro Sugimura, Shigefumi Fukui, Hiroaki Shimokawa, Kei TakaseAbstractPulmonary tumor thrombotic microangiopathy (PTTM) is a specific type of tumor embolism in the small and medium pulmonary arteries, leading to rapid progressive pulmonary hypertension. Antemortem diagnosis of PTTM is extremely difficult. We encountered three patients who were histopathologically or clinically diagnosed with PTTM. In all cases, lung perfused blood volume (PBV) images on dual-energy computed tomography (CT) demons...
Source: European Journal of Radiology Open - Category: Radiology Source Type: research
ConclusionIt is preferable to perform CCTA in young patients with cardiac symptoms, especially in Asian and Middle Eastern countries even of the CAC score is zero.
Source: European Journal of Radiology Open - Category: Radiology Source Type: research
Publication date: Available online 28 January 2020Source: European Journal of RadiologyAuthor(s): Satoru Morita, Yuko Ogawa, Takahiro Yamamoto, Kumi Kamoshida, Hiroshi Yamazaki, Kazufumi Suzuki, Shuji Sakai, Motoki Kunihara, Toshio Takagi, Kazunari TanabeAbstractPurposeTo evaluate the image quality of early postoperative CT angiography with low contrast material and radiation dose using model-based iterative reconstruction (FIRST) for screening pseudoaneurysms after partial nephrectomy.MethodsCT angiography was obtained before surgery using conventional iterative dose reduction reconstruction (AIDR 3D) with 120 kVp and 600...
Source: European Journal of Radiology - Category: Radiology Source Type: research
Condition:   Chorioretinitis Interventions:   Procedure: Intravitreal injection;   Diagnostic Test: Fluorescent angiography;   Diagnostic Test: Visometry;   Diagnostic Test: Refractometry;   Diagnostic Test: Slit lamp examination;   Diagnostic Test: Ophthalmoscopy;   Diagnostic Test: OKT Sponsors:   The Filatov Institute of Eye Diseases and Tissue Therapy;   Odessa National Medical University;   Mykolaiv Region Ophthalmogical Hospital;   Central ...
Source: - Category: Research Source Type: clinical trials
CONCLUSION: When visual functional signs appear during adult Still's disease, it is necessary to evoke Putscher-like retinopathy, and to ask for an ophthalmological expertise. PMID: 31983549 [PubMed - as supplied by publisher]
Source: Revue de Medecine Interne - Category: Internal Medicine Tags: Rev Med Interne Source Type: research
Publication date: June 2020Source: Interdisciplinary Neurosurgery, Volume 20Author(s): Baha Eldin Adam, Emin Mehmet Eminoglu, Zeynep Karaoglu, Naci BalakAbstractRecent studies suggest that a total ischemic brain tissue volume>300 cm3 observed on CT is a significant indicator of an unfavorable outcome with a sensitivity of 100% after DC in patients with malignant ischemic stroke. In this article, we reported a 61-year-old male patient with poor preoperative clinical status and most predictive factors pointed to an unfavorable outcome who nonetheless demonstrated an acceptable functional recovery after DC. On cranial...
Source: Interdisciplinary Neurosurgery - Category: Neurosurgery Source Type: research
Authors: Wang Y, Xuan Z, Zheng X, Han R, Zhou L, Liu H, Liu Y Abstract PURPOSE: To evaluate the effect of transcatheter arterial chemoembolization (TACE) under the guidance of contrast-enhanced ultrasound (CEUS) in patients with advanced hepatocellular carcinoma (HCC). METHODS: One hundred and sixty patients with HCC admitted to Cangzhou Central Hospital from April 2015 to April 2017 were enrolled. The clinical data were retrospectively analyzed. Seventy-five patients who underwent TACE according to CEUS results were selected as the observation group. The remaining 85 cases that underwent digital subtraction au...
Source: Journal of B.U.ON. - Category: Cancer & Oncology Tags: J BUON Source Type: research
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