Experiment research on the treatment of sevoflurane to human breast cancer cell with high intensity focused ultrasound.

Experiment research on the treatment of sevoflurane to human breast cancer cell with high intensity focused ultrasound. Panminerva Med. 2019 Dec 13;: Authors: Zhang M, Wang L, Liu Q, Zhong X, Wang Z, Tian Z PMID: 31833732 [PubMed - as supplied by publisher]
Source: Panminerva Medica - Category: General Medicine Tags: Panminerva Med Source Type: research

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CONCLUSIONS: Bifidobacterium can cause changes in collagen fiber content, acoustic velocity and attenuation in the tumor tissue and reduce the EEF of HIFU irradiation, thereby improving the efficacy of HIFU irradiation. PMID: 31640961 [PubMed - in process]
Source: Journal of Southern Medical University - Category: Universities & Medical Training Authors: Tags: Nan Fang Yi Ke Da Xue Xue Bao Source Type: research
Medical device companies attempting to market a new treatment in the U.S. often make the erroneous assumption that winning FDA approval is the final destination, and success is theirs. In fact, going through the regulatory process is only the halfway point. The grueling path from FDA approval to reimbursement is like a treacherous walk through Death Valley and many companies don’t make it through. In this case study, I discuss the trials and triumphs of bringing robotic high intensity focused ultrasound (HIFU), a non-invasive procedure for localized prostate cancer, to the U.S.&Aci...
Source: MDDI - Category: Medical Devices Authors: Tags: Regulatory and Compliance Business Source Type: news
AbstractRecently, a number of new minimally invasive image-guided percutaneous ablation treatments, including cryoablation, radiofrequency ablation, microwave ablation, high-intensity focused ultrasound, laser ablation, and irreversible electroporation have been developed. Several studies have shown the feasibility and safety of these cryoablation therapies for the treatment of benign breast tumors and small invasive breast cancer. Although the complete response rate of cryoablation for breast cancer is reported to be relatively good, most studies enrolled a small number of patients, and so reliable conclusions could not b...
Source: International Journal of Clinical Oncology - Category: Cancer & Oncology Source Type: research
With improvements in breast imaging, mammography, ultrasound and minimally invasive interventions, the detection of early breast cancer, non-invasive cancers, lesions of uncertain malignant potential, and benign lesions has increased. However, with the improved diagnostic capabilities comes a substantial risk of false-positive benign lesions and vice versa false-negative malignant lesions. A statement is provided on the manifestation, imaging, and diagnostic verification of isolated benign breast tumours that have a frequent manifestation, in addition to general therapy management recommendations. Histological evaluation o...
Source: Breast Care - Category: Cancer & Oncology Source Type: research
ConclusionsThe obtained results demonstrated that the focal error observed during the breast cancer HIFU treatment is highly dependent on the structure of fibroglandular tissue. The optimal arrangement of the transducer to the target can be obtained by minimizing the local acoustic inhomogeneity before the breast cancer HIFU treatment.
Source: Journal of Therapeutic Ultrasound - Category: Radiology Source Type: research
Condition:   Breast Cancer, Invasive Ductal Intervention:   Device: Philips Sonalleve® MR-HIFU Breast Therapy System Sponsor:   Kantonsspital Winterthur KSW Not yet recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
This work reports that when PEG-lipid-shelled microbubbles with fluorocarbon interior (C4F10, C5F12, or C6F14) are subjected to ultrasound pulses, they produce metastable, fluid-filled nanoparticles that can be re-imaged upon administration of HIFU. The nanoparticles produced by destruction of the microbubbles (MBNPs) are of 150 nm average diameter and can be re-imaged for up to an hour after creation for C 4F10, and for at least one day for C5F12. The active species were found to be fluid (gas or liquid) filled nanoparticles rather than lipid debris. The acoustic droplet vaporization threshold of the nanoparticles was fou...
Source: Theranostics - Category: Molecular Biology Authors: Tags: Research Paper Source Type: research
Most people think of ultrasound as an imaging modality. Yet, there are many other clinical uses for the high frequency soundwaves. Focused ultrasound waves can promote the opening of the blood-brain barrier, and they can be used to ablate fibroids, a...
Source: Medgadget - Category: Medical Devices Authors: Tags: Medicine News Source Type: blogs
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