The Loss of SMAD4/DPC4 Expression Associated with a Strongly Activated Hedgehog Signaling Pathway Predicts Poor Prognosis in Resected Pancreatic Cancer

Conclusion: Loss of SMAD4 associated with a strongly activated Shh pathway resulted in poor survival outcomes in patients with resected PDAC.

Source: Journal of Cancer - December 14, 2019 Category: Cancer & Oncology Authors: Jin-Zhi Xu, Wen-Quan Wang, Wu-Hu Zhang, Hua-Xiang Xu, He-Li Gao, Shi-Rong Zhang, Chun-Tao Wu, Shuo Li, Hao Li, Jin Xu, Xian-Jun Yu, Liang Liu Tags: Research Paper Source Type: research