SYT12 plays a critical role in oral cancer and may be a novel therapeutic target

Synaptotagmin12 (SYT12) has been well characterized as the regulator of transmitter release in the nervous system, however the relevance and molecular mechanisms of SYT12 in oral squamous cell carcinoma (OSCC) are not understood. In the current study, we investigated the expression of SYT12 and its molecular biological functions in OSCC by quantitative reverse transcriptase polymerase chain reaction, immunoblot analysis, and immunohistochemistry. SYT12 were up-regulated significantly in OSCC-derived cell lines and primary OSCC tissue compared with the normal counterparts (P
Source: Journal of Cancer - Category: Cancer & Oncology Authors: Tags: Research Paper Source Type: research

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Men’s sexual health and wellness company, Morari Medical is using neuromodulation for its wearable device to help treat premature ejaculation (PE). The Maple Grove, MN-based company debuted a prototype of the patch-like device at the Consumer Electronics Show in Las Vegas earlier this month. Morari was one of 10 companies in the emerging sextech market to have a presence at the show. Jeff Bennett, the company’s founder and CEO spoke with MD+DI about the Morari Medical and its mission. “Specifically, we’re trying to address the medical condition of PE, ...
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Source: Progress in Neuro Psychopharmacology and Biological Psychiatry - Category: Psychiatry Source Type: research
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