Dual role of KRT17: development of papillary renal cell tumor and progression of conventional renal cell carcinoma
In conclusion, the continuous expression of KRT17 from emerging fetal kidney tubules and microscopic pre-neoplastic lesions towards papillary renal cell tumors and its neo-expression in aggressive growing conventional renal cell carcinomas reflects the multiple function of KRT17 in kidney cancers with distinct natural history. This should be taken into account in clinical managements and therapy.
Source: Journal of Cancer - Category: Cancer & Oncology Authors: Donat Peter Sarlos, Maria V Yusenko, Lehel Peterfi, Arpad Szanto, Gyula Kovacs Tags: Short Research Communication Source Type: research
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