LOX inhibition downregulates MMP-2 and MMP-9 in gastric cancer tissues and cells

Conclusions: LOX inhibition can inhibit the expression and enzyme activity of MMP-2 and MMP-9 in gastric cancer tissues and cells, and the probable mechanism is through its effects on the PDGF-PDGFR signaling pathway.

Source: Journal of Cancer - December 14, 2019 Category: Cancer & Oncology Authors: Lei Zhao, Haiya Niu, Yutao Liu, Lei Wang, Ning Zhang, Gaiqiang Zhang, Rongqing Liu, Mei Han Tags: Research Paper Source Type: research