Perioperative restrictive versus goal-directed fluid therapy for adults undergoing major non-cardiac surgery.

CONCLUSIONS: Based on very low-certainty evidence, we are uncertain whether RFT is inferior to GDFT in selected populations of adults undergoing major non-cardiac surgery. The evidence is based mainly on data from studies on abdominal surgery in a low-risk population. The evidence does not address higher-risk populations or other surgery types. Larger, higher-quality RCTs including a wider spectrum of surgery types and a wider spectrum of patient groups, including high-risk populations, are needed to determine effects of the intervention.
PMID: 31829446 [PubMed - in process]

Source: Cochrane Database of Systematic Reviews - December 11, 2019 Category: General Medicine Authors: Wrzosek A, Jakowicka-Wordliczek J, Zajaczkowska R, Serednicki WT, Jankowski M, Bala MM, Swierz MJ, Polak M, Wordliczek J Tags: Cochrane Database Syst Rev Source Type: research