Clinical features of genetically-confirmed patients with primary hyperoxaluria identified by clinical indication versus familial screening

Primary hyperoxaluria is a rare monogenic disorder characterized by excessive hepatic production of oxalate leading to recurrent nephrolithiasis, nephrocalcinosis and progressive kidney damage. Most patients with primary hyperoxaluria are diagnosed after clinical suspicion based on symptoms. Since some patients are detected by family screening following detection of an affected family member, we compared the clinical phenotype of these two groups. Patients with primary hyperoxaluria types 1, 2, and 3 enrolled in the Rare Kidney Stone Consortium Primary Hyperoxaluria Registry were retrospectively analyzed following capture of clinical and laboratory results in the Registry.
Source: Kidney International - Category: Urology & Nephrology Authors: Tags: Clinical Investigation Source Type: research

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Condition:   Kidney Stone Intervention:   Other: Data extraction Sponsor:   Agnieszka Pozdzik Recruiting
Source: - Category: Research Source Type: clinical trials
This study aims to investigate whether 3D-MSD can predict ureteroscopic lithotripsy outcome. We retrospectively identified 218 patients who underwent ureteroscopic lithotripsy for kidney stones (n = 135) and ureteral stones (n = 83) between February 2011 and April 2017 with pretreatment non-contrast computed tomography (NCCT) at our hospital. Stone volume and 3D-MSD were automatically measured using high functional viewer. Logistic regression analysis was performed to identify factors contributing to treatment failur e. Treatment failure was determined as residual fragments ≥ 4&...
Source: Urolithiasis - Category: Urology & Nephrology Source Type: research
(Natural News) The prevalence and recurrence rates of kidney stone disease (urolithiasis) are increasing globally. This health problem affects 12 percent of the world’s population, with more men suffering from it than in women. Despite recent medical advancements, there are still very limited options when it comes to effective anti-urolithiasis drugs. But in a recent study...
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ConclusionThe results of this randomized, double-blind, placebo-controlled trial suggest that PVB should be considered an effective strategy to reduce opioid requirement and improve pain control for patients undergoing PCNL.
Source: World Journal of Urology - Category: Urology & Nephrology Source Type: research
LIFESTYLE RISK FACTORS AND BONE MASS IN RECURRENT STONE-FORMING PATIENTS: A CROSS-SECTIONAL STUDY IN 144 SUBJECTS. Acta Clin Croat. 2019 Sep;58(3):439-445 Authors: Marić I, Kizivat T, Smolić M, Smolić R, Opačak-Bernardi T, Šolić K, Roguljić H, Milas Ahić J, Tucak A, Mihaljević I Abstract Patients with urolithiasis, particularly hypercalciuria, may have reduced bone mineral density (BMD). There are numerous risk factors contributing to reduction of BMD such as advanced age, sedentary lifestyle, smoking, low calcium intake, etc. The aim of our study was to investigate the association of li...
Source: Acta Clinica Croatica - Category: General Medicine Tags: Acta Clin Croat Source Type: research
Phys. Chem. Chem. Phys., 2020, Accepted Manuscript DOI: 10.1039/C9CP06499K, PaperShanthil Madhavan, Sandeep K, P K Sajith Precipitation and dissolution of calcium oxalate monohydrate (CaOx) crystals are relevant due to their major role in kidney stone diseases. To such an extent, small molecules and ions can act... The content of this RSS Feed (c) The Royal Society of Chemistry
Source: RSC - Phys. Chem. Chem. Phys. latest articles - Category: Chemistry Authors: Source Type: research
In conclusion, urinary SS varies throughout the day, being higher for CaOx and CaP at night, and in the early morning for UA. For CaOx and UA, the overnight and 12–4 pm urine samples, respectively, contribute most to the variability ob served in the SS of 24-h urine.
Source: Urolithiasis - Category: Urology & Nephrology Source Type: research
Conditions:   Shared Decision-making;   Kidney Stone;   Emergencies;   Radiation Exposure;   Communication Interventions:   Behavioral: Decision Aid;   Other: Standardized Educational Material (informational pamphlet) Sponsors:   Baystate Medical Center;   Agency for Healthcare Research and Quality (AHRQ) Recruiting
Source: - Category: Research Source Type: clinical trials
PMID: 31958838 [PubMed - in process]
Source: Annals of Internal Medicine - Category: Internal Medicine Authors: Tags: Ann Intern Med Source Type: research
Ureteritis cystica is rare, benign entity that associates with chronic urothelial irritation such as recurrent urinary tract infection or nephrolithiasis. It is often diagnosed incidentally on routine imaging or ureteroscopy in asymptomatic individuals. In this case report, we present the retrograde pyelogram and ureteroscopy images of a rare case of extensive unilateral ureteritis cystica in a 78-year-old female presenting for elective stone surgery.
Source: Urology - Category: Urology & Nephrology Authors: Source Type: research
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