Boys born small at heightened risk of infertility as adults

Mother ’s health and lifestyle during pregnancy may be important factors in restricting foetal growth and reproductive capacity, suggest researchers Related items fromOnMedica Inducing labour in late pregnancies is safer approach Monitor women better to cut stillbirth rates Doctors demand action on drinking in pregnancy Fetal exposure to nicotine linked to later obesity Exercise throughout pregnancy is safe and beneficial
Source: OnMedica Latest News - Category: UK Health Source Type: news

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Publication date: Available online 10 January 2020Source: Mutation Research/Genetic Toxicology and Environmental MutagenesisAuthor(s): Michael Fenech, Nina Holland, Micheline Kirsch-Volders, Lisbeth E. Knudsen, Karl-Heinz Wagner, Helga Stopper, Siegfried Knasmueller, Claudia Bolognesi, Randa El-Zein, Stefano BonassiAbstractThe “Micronuclei and Disease” workshop was organized by the HUMN Project consortium and hosted by the European Environmental Mutagen and Genomics Society at their annual meeting in Rennes, France, on 23 May 2019. The program of the workshop focused on addressing the emerging evidence linking ...
Source: Mutation Research Genetic Toxicology and Environmental Mutagenesis - Category: Genetics & Stem Cells Source Type: research
This study raises serious concerns about whether we’ve been careful enough about the safety of this chemical,” said Patricia Hunt, a professor of molecular bioscience at Washington State, and a corresponding author of the paper, in a statement. Despite how huge the difference, the results are not getting much evident pushback from other researchers in the field. “It honestly blew my mind—not because I don’t believe it, but because it appears to be true,” says Lori Hoepner, assistant professor of environmental and occupational health sciences at SUNY Downstate School of Public Health. &ld...
Source: TIME: Health - Category: Consumer Health News Authors: Tags: Uncategorized bisphenol a BPA endocrine disruptor Environment Environmental Health Source Type: news
ConclusionOur findings support increased paternal BMI negatively affecting pregnancy and child health outcomes. Future studies must include or adjust for paternal contributions, as the longstanding assumption that only maternal factors are relevant is likely to have considerably confounded prior work.
Source: Obesity Research and Clinical Practice - Category: Eating Disorders & Weight Management Source Type: research
ConclusionObesity is closely associated with primary infertility and PCOD. Menstrual abnormalities associated with PCOD significantly improve after bariatric surgery with significant improvement in fertility along with maternal outcomes.
Source: Obesity Surgery - Category: Surgery Source Type: research
Purpose of review In recent years, new studies have investigated the role and influence of sleep on female fertility and early pregnancy outcomes, providing a growing body of knowledge demonstrating how regulation by sleep of hormones are important to reproduction, and how disruptions in sleep, circadian rhythms, and genes regulating circadian rhythmicity can negatively impact fertility and early pregnancy outcomes. This review aims to summarize the most recent research on the relationship among circadian rhythms, fertility, and early pregnancy outcomes in women, and to explore possible fertility interventions. Recent f...
Source: Current Opinion in Endocrinology, Diabetes and Obesity - Category: Endocrinology Tags: REPRODUCTIVE ENDOCRINOLOGY: Edited by Wendy Kuohung Source Type: research
ConclusionEndometrial cancer, specifically type I endometrioid adenocarcinoma and its precursor lesions are strongly associated with unopposed estrogen states such as polycystic ovarian syndrome (PCOS), obesity as well as nulliparity. Patients seeking assisted reproductive technologies make up a subset of these patients and strongly desire to maintain their fertility. Progesterone therapy for select patients may be a safe and effective temporary treatment for endometrial carcinoma and atypical precursor lesions prior to starting IVF-ET. IVF-ET is very effective in treating such patients.
Source: Journal of Minimally Invasive Gynecology - Category: OBGYN Source Type: research
Abstract The increasing occurrence of obesity has become a significant public health concern. Obese individuals have higher prevalence of heart disease, stroke, osteoarthritis, diabetes, and reproductive disorders. Reproductive problems include menstrual irregularities, pregnancy complications, and infertility due to anovulation, in women, and lower testosterone and diminished sperm count, in men. In particular, obese women have reduced levels of both gonadotropin hormones and, in obese men, lower testosterone is accompanied by diminished luteinizing hormone. Together these findings indicate central dysregulation ...
Source: Endocrinology - Category: Endocrinology Authors: Tags: Endocrinology Source Type: research
Does it make sense, medically or ethically, when fertility clinics refuse to treat prospective mothers they consider too large?
Source: NYT Health - Category: Consumer Health News Authors: Tags: In Vitro Fertilization Weight Infertility Pregnancy and Childbirth Women and Girls Obesity Fertility Drugs Source Type: news
Publication date: Available online 15 May 2019Source: Best Practice &Research Clinical Endocrinology &MetabolismAuthor(s): Hanna Hürter, Shane Vontelin van Breda, Lenka Vokalova, Marlene Brandl, Marc Baumann, Irene Hösli, Evelin Annegret Huhn, Christian De Geyter, Simona W. Rossi, Olav LapaireAbstractAlthough an increased risk of pre-eclampsia in pregnancies conceived after infertility treatment has been reported, it remains unknown whether preconceptional minimalisation of known risk factors would help in preventing pre-eclamsia. Obesity and preconceptional blood pressure are discussed as major risks for...
Source: Best Practice and Research Clinical Endocrinology and Metabolism - Category: Endocrinology Source Type: research
AbstractPurposeTo assess the effect of body mass index (BMI) on morphokinetic parameters of human embryos evaluated with time-lapse technology during in vitro culture.MethodsA retrospective analysis of ART cycles utilizing time-lapse technology was undertaken to assess the potential impact of maternal BMI on morphokinetic and static morphological parameters of embryo development. The cohort of patients was divided into four groups: 593 embryos from 128 underweight women in group A; 5248 embryos from 1107 normal weight women in group B; 1053 embryos from 226 overweight women in group C; and 286 embryos from 67 obese women i...
Source: Journal of Assisted Reproduction and Genetics - Category: Reproduction Medicine Source Type: research
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