Neuroprotective effects of Bacopa monnieri in Parkinson ’s disease model

We examined the neuro-protective effects ofBacopa monnieri (BM) in regulating neuroinflammation. Administration ofBM suppressed the level of pro-inflammatory cytokines, decreased the levels of α-synuclein, and reduced reactive oxygen species (ROS) generation in PD animal model. Pre-treatment of BM showed more prominent results as compare to co- and post-treatment. Results suggest that Bacopa can limit inflammation in the different areas of brain, thus, offers a promising source of novel therapeutics for the treatment of many CNS disorders.
Source: Metabolic Brain Disease - Category: Neurology Source Type: research