Consensus of the Hellenic Headache Society on the diagnosis and treatment of migraine

AbstractMore than 0.6 million people suffer from disabling migraines in Greece causing a dramatic work loss, but only a small proportion of migraineurs attend headache centres, most of them being treated by non-experts. On behalf of the Hellenic Headache Society, we report here a consensus on the diagnosis and treatment of adult migraine that is based on the recent guidelines of the European Headache Federation, on the principles of Good Clinical Practice and on the Greek regulatory affairs. The purposes are three-fold: (1) to increase awareness for migraine in Greece; (2) to support Greek practitioners who are treating migraineurs; and (3) to help Greek migraineurs to get the most appropriate treatment. For mild migraine, symptomatic treatment with high dose simple analgesics is suggested, while for moderate to severe migraines triptans or non-steroidal anti-inflammatory drugs, or both, should be administered following an individually tailored therapeutic strategy. A rescue acute treatment option should always be advised. For episodic migraine prevention, metoprolol (50 –200 mg/d), propranolol (40–240 mg/d), flunarizine (5–10 mg/d), valproate (500–1800 mg/d), topiramate (25–100 mg/d) and candesartan (16–32 mg/d) are the drugs of first choice. For chronic migraine prevention topiramate (100-200 mg/d), valproate (500–1800 mg/d), flunariz ine (5–10 mg/d) and venlafaxin...
Source: The Journal of Headache and Pain - Category: Neurology Source Type: research

Related Links:

ConclusionThese results support the theory that underlying neurometabolite levels may be unique in different pain conditions and therefore representative of biomarkers for specific pain conditions.
Source: NeuroImage - Category: Neuroscience Source Type: research
With all the advances in modern medicine, it can be easy to wonder if there is a medication to stop drinking. Unfortunately, getting sober from alcohol isn’t as easy as simply taking medication. In addition to medication, therapy is required for the best long-term results, as well as support from loved ones and ongoing aftercare. However, there are some medications to help along in the process to stop withdrawal symptoms, block cravings, and create an aversion to alcohol. It is important to not rely only on medication to stop drinking. A commitment to behavioral therapy, holistic therapy, family involvement, self-ca...
Source: Cliffside Malibu - Category: Addiction Authors: Tags: Alcohol Alcohol Rehab Information Alcoholism Detox Resources for Alcohol and Drugs/Opiates alcohol abuse alcohol dependence alcohol detox alcohol treatment alcohol treatment center alcohol treatment facility Source Type: blogs
ConclusionsOur results indicated that the P2X4R contributes to the central sensitization of CM by releasing BDNF and promoting TNC neuronal hyper-excitability. Blocking microglia P2X4R-BDNF signalling may have an effect on the prevention of migraine chronification.
Source: The Journal of Headache and Pain - Category: Neurology Source Type: research
Source: Journal of Pain Research - Category: Anesthesiology Tags: Journal of Pain Research Source Type: research
ConclusionThe pooled estimated prevalence of headache among patients with epilepsy was considerably high (48.4%). Screening and appropriate management of headaches among patients with epilepsy are warranted.
Source: The Journal of Headache and Pain - Category: Neurology Source Type: research
Chronic migraine is a highly disabling disease with a great impact on socioeconomic functioning and quality of life of migraine patients. Chronic migraine usually evolves from episodic migraine that gradually increases in attack frequency, supporting the view of migraine as a spectrum disorder. Pathophysiological mechanisms responsible for migraine chronification are not fully understood. Likewise episodic migraine, chronic migraine patients show widespread functional and structural alterations of cortical and subcortical pain-related brain areas. However, chronic migraine patients experience a more pronounced dysfunction ...
Source: Frontiers in Neurology - Category: Neurology Source Type: research
AbstractPurpose of ReviewPost dural puncture headache (PDPH) is a relatively common complication which may occur in the setting of inadvertent dural puncture (DP) during labor epidural analgesia and during intentional DP during spinal anesthetic placement or diagnostic lumbar puncture. Few publications have established the long-term safety of an epidural blood patch (EBP) for the treatment of a PDPH.Recent FindingsThe aim of this pilot study was to examine the association of chronic low back pain (LBP) in patients who experienced a PDPH following labor analgesia and were treated with an EBP. A total of 146 patients were co...
Source: Current Pain and Headache Reports - Category: Neurology Source Type: research
Coherent, unambiguous and stable perceptual experiences result from the ability to merge concurrent information provided by different senses26,43,50,72. Multisensory integration occurs when stimuli from different sensory systems are combined in close temporal or spatial proximity, improving their detection2,12,25,50,76. However, we experience illusory percepts whenever sensory inputs from different modalities are incoherent45,53,76,80,90. Crossmodal illusions represent useful paradigms to assess how multisensory integration affects sensory perception in healthy and pathological conditions17,77,78, as shown by the Sound-Ind...
Source: The Journal of Pain - Category: Materials Science Authors: Tags: Original Reports Source Type: research
CONCLUSIONS: Comorbid GAD + back pain and GAD + migraine have a unique association with nonmedical opioid use in Canadians compared to GAD only, and chronic pain multimorbidity may be driving this relationship. Results emphasize the need for screening for substance misuse and prescription access in the context of GAD and comorbid chronic pain. PMID: 31896273 [PubMed - as supplied by publisher]
Source: Canadian Journal of Psychiatry - Category: Psychiatry Authors: Tags: Can J Psychiatry Source Type: research
This study with nationwide coverage showed no evidence of a causal link between HPV vaccination and diffuse autonomic symptoms leading to hospital contact. PMID: 31899791 [PubMed - as supplied by publisher]
Source: Am J Epidemiol - Category: Epidemiology Authors: Tags: Am J Epidemiol Source Type: research
More News: Botox | Chronic Pain | Effexor | Greece Health | Headache | Inderal | Migraine | Neurology | Pain | Topamax | Toprol