Neuraminidase inhibitors for influenza-like illness in primary care
Publication date: Available online 12 December 2019Source: The LancetAuthor(s): Nelson Lee, Michael Ison
ConclusionCommunity and co-worker contacts are important sources of viral respiratory illness in healthcare personnel while exposure to patients with recognized respiratory infections is not associated. The comparatively low risk associated with direct patient contact may reflect transmission related to asymptomatic patients or unrecognized infections.
This report describes CDC's and Louisiana health officials'investigation of the state's early and intense flu activity in the fall of 2019
This article explores some the most up-to-date influenza literature and research. It discusses how nurses and other health professionals can use this evidence in order to help them mitigate the consequences of influenza.
Flu season is always unpredictable. Different viral strains circulate each year, which makes forecasting the disease’s spread—and formulating the annual flu vaccine—an educated guessing game. Even so, the 2019-2020 flu season has been particularly unusual. Influenza B, the viral strain that usually circulates toward the end of flu season, instead emerged first this year, shifting usual transmission patterns. A vaccine mismatch and reduced immunity to influenza B may have contributed to the early and severe start of this flu season. What does that mean for the months ahead? TIME asked Lynnette Brammer, an ...
Doubling the dose of influenza vaccine for pregnant women with HIV moderately improves immunogenicity compared to a single flu shot, but response remains well below that of pregnant women without HIV, a clinical trial shows.Reuters Health Information
Authors: Shaim H, McCaffrey P, Trieu JA, DeAnda A, Yates SG Abstract Desialylation of platelets results in platelet clearance by the Ashwell-Morrell Receptors (AMR) found on hepatocytes. Studies suggest that oseltamivir phosphate inhibits human sialidases, enzymes responsible for desialylation, extending the lifespan of circulating platelets. We thus evaluated, the effects of oseltamivir on platelet count (PC) following treatment. Of the 385 patients evaluated for influenza, 283 (73.5%) were influenza-infected. Of the 283 infected patients, 241 (85.2%) received oseltamivir (I + O+) while 42 patients did n...
Four strains of the influenza virus have been identified through lab tests as circulating across the United States so far this flu season. This year's vaccine has two of them, but experts say vaccination still helps.
We conducted a retrospective study to identify the risk factors for pneumonia in hospitalized pediatric patients with influenza B infection. Receiving oseltamivir within the first 48 hours of onset and frequent cough was respectively considered as a protective factor and a risk factor for the influenza B virus-associated pneumonia in hospitalized pediatric patients. Early administration of oseltamivir can reduce the risk of influenza B virus-associated pneumonia.
Conclusions: Corticosteroid treatment in influenza is associated with increased mortality and hospital-acquired infection, but the evidence relates mainly to high corticosteroid doses and is of low quality with potential confounding by indication a major concern.
Influenza season is still in full swing and children are especially hard hit, in part as a result of a vaccine that is poorly matched to the currently predominant strain.Medscape Medical News