Oral Oncolytics: Part 1—Financial, Adherence, and Management Challenges

The management of patients receiving treatment with oral oncolytics presents challenges such as cost, adherence, monitoring of side effects, and safe handling.
Source: Cancer Network - Category: Cancer & Oncology Source Type: news

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Abstract Retrospective analysis has already shown correlation between severe Chronic Periodontitis (CP) cases with human papiloma virus (HPV). Hence, we aimed to explore deep-seated infected granulation tissue removed during periodontal flap surgery procedures for residential bacterial species between HPV+ and HVP- CP cases, which may serve as good predisposition marker for oral cancer. All CP-granulation samples showed the prominence of Firmicutes, Proteobacteria, and Bacteroidetes phyla with an abundance of gram negative anaerobes, except Streptococcus. In Beta diversity nonmetric multidimensional scaling plot, ...
Source: Biomed Res - Category: Research Authors: Tags: Biomed Res Int Source Type: research
CONCLUSIONS: This paper presents five cases and a radiographic inventory to illustrate disturbances of dental development associated with chemotherapy and radiotherapy therapy in children. Medical and dental professionals involved in the treatment of cancer survivors are relatively unaware of the dental consequences of radiation therapy and the age dependency of specific regional effects. These effects can be severe, with great impact on quality of life. Further research in this area could help improve planning of radiation therapy for children, potentially preventing or limiting dental or maxillofacial sequelae. PMID:...
Source: Dentomaxillofacial Radiology - Category: Radiology Tags: Dentomaxillofac Radiol Source Type: research
LangmuirDOI: 10.1021/acs.langmuir.9b03001
Source: Langmuir - Category: Chemistry Authors: Source Type: research
ConclusionsEarly feeding and discharge for total or proximal gastrectomy is feasible and safe as long as it is carefully applied to high-risk patients, but we must be aware of the relatively higher readmission rate of this patient group.
Source: Annals of Surgical Oncology - Category: Cancer & Oncology Source Type: research
AbstractPurpose of ReviewMost drugs are given by the oral route. Oral intake allows direct contact between the drug and the entire GI tract mucosa, exposing it to potential topical damage until absorption. Medication-induced GI symptoms and lesions are therefore commonly encountered in clinical practice. This review will examine the most common drugs or classes of drugs affecting small bowel function and/or structure.Recent FindingsSince non-steroidal anti-inflammatory drugs (NSAIDs) are among the most widely used medicines, NSAID enteropathy is highly prevalent and brings about considerable morbidity. Antimicrobials and p...
Source: Current Gastroenterology Reports - Category: Gastroenterology Source Type: research
This article describes ossification of the corresponding vascular pedicle after soft tissue transfer with the lateral upper arm free flap and microsurgical anastomosis in oral cancer treatment. Similar findings in the context of the lateral upper arm free flap have never been reported in the literature; however, it is important for surgeons to know that pedicle ossification can occur. This knowledge may be helpful to avoid erroneous diagnosis of the ossification as a sign of tumor relapse/recurrence as well as to anticipate potential difficulties in the surgical approach in cases requiring reentry of the reconstructed regi...
Source: Annals of Plastic Surgery - Category: Cosmetic Surgery Tags: Microsurgery Source Type: research
By Sandee LaMotte, CNN (CNN) — If certain vegetables have always made you gag, you may be more than a picky eater. Instead, you might be what scientists call a “super-taster:” a person with a genetic predisposition to taste food differently. Unfortunately, being a super-taster doesn’t make everything taste better. In fact, it can do the opposite. Super-tasters are extremely sensitive to bitterness, a common characteristic of many dark green, leafy veggies such as broccoli, cauliflower, cabbage and Brussels sprouts, to name a few. “The person who has that genetic propensity gets more of the sul...
Source: WBZ-TV - Breaking News, Weather and Sports for Boston, Worcester and New Hampshire - Category: Consumer Health News Authors: Tags: Health News CNN Source Type: news
(The Mount Sinai Hospital / Mount Sinai School of Medicine) Recent study found that an effective blood cancer treatment was associated with weight gain, obesity, and increased systolic blood pressure.
Source: EurekAlert! - Medicine and Health - Category: International Medicine & Public Health Source Type: news
(The Mount Sinai Hospital / Mount Sinai School of Medicine) Recent study found that an effective blood cancer treatment was associated with weight gain, obesity, and increased systolic blood pressure.
Source: EurekAlert! - Cancer - Category: Cancer & Oncology Source Type: news
Recent study found that an effective blood cancer treatment was associated with weight gain, obesity, and increased systolic blood pressure(PRWeb November 12, 2019)Read the full story at https://www.prweb.com/releases/mount_sinai_researchers_examine_the_metabolic_effects_of_an_oral_blood_cancer_drug/prweb16714864.htm
Source: PRWeb: Medical Pharmaceuticals - Category: Pharmaceuticals Source Type: news
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