Cautionary statement issued in response to radioactive iodine therapy study

The Society for Endocrinology and the British Thyroid Association have issued a joint cautionary statement in response to a recent paper about the link between radioactive iodine therapy and cancer mortality in people with hyperthyroidism.Healio
Source: Society for Endocrinology - Category: Endocrinology Source Type: news

Related Links:

J Clin Endocrinol Metab. 2021 Sep 23:dgab700. doi: 10.1210/clinem/dgab700. Online ahead of print.ABSTRACTRadioactive iodine has been considered a safe and effective therapeutic option for hyperthyroidism secondary to Graves' disease and autonomously functioning thyroid nodules since the mid-20th century. The question of whether I-131 at the doses used for hyperthyroidism might increase the risk of cancer has been investigated in a number of observational cohort studies over the years, with the preponderance of evidence being reassuring as to its safety. In particular, the 1998 Cooperative Thyrotoxicosis Therapy Follow-up S...
Source: Clinical Genitourinary Cancer - Category: Cancer & Oncology Authors: Source Type: research
The role of thyroid hormones (THs) in the cardiovascular (CV) system, through several direct and indirect effects is recognized. Even very small modification in TH levels (as those observed in subclinical hypothyroidism or hyperthyroidism, and low triiodothyronine syndrome) may adversely affect the CV system, whereas thyroid hormones benefit the CV system and improve the prognosis. There is also evidence of vitamin D effects on cardiometabolic disease (e.g., through modulation of endothelial and smooth muscle cell activity, renin-angiotensin-aldosterone system, nitric oxide, oxidative stress, and inflammatory response), as...
Source: Frontiers in Physiology - Category: Physiology Source Type: research
We present two young, Caucasian female patients aged 29 and 13 years who were each diagnosed with a toxic nodule categorised as benign and indeterminate respectively. They underwent hemithyroidectomy after being rendered euthyroid, however their histology unexpectedly revealed differentiated follicular cancer. Despite thyroid cancer being rare in patients with toxic adenomas, it should be considered when planning treatment, especially if there are risk factors for cancer, or suspicious features on ultrasound examination. A review of the literature shows that compared with adenomas in euthyroid patients, patients in this gr...
Source: Annals of the Royal College of Surgeons of England - Category: Surgery Authors: Source Type: research
CONCLUSION: Evidence from observational studies suggests that postmenopausal women treated with TSH suppression therapy are at risk for lower BMD. Attention should be paid to long-term skeletal safety in DTC survivors.PMID:34302730 | DOI:10.1210/clinem/dgab539
Source: The Journal of Clinical Endocrinology and Metabolism - Category: Endocrinology Authors: Source Type: research
This article highlights thyroid carcinoma in the pediatric population and reviews the current testing and management options. [Pediatr Ann. 2020;50(7):e282-e285.].PMID:34264794 | DOI:10.3928/19382359-20210621-01
Source: Pediatric Annals - Category: Pediatrics Authors: Source Type: research
More News: Cancer | Cancer & Oncology | Endocrinology | Hyperthyroidism | Iodine | Study | Thyroid | Thyroid Cancer | UK Health