New Study Shakes Up Thinking on Hormone Replacement Therapy
Publication date: Available online 15 February 2020Source: Reproductive BioMedicine OnlineAuthor(s): Mehtap Polat, Sezcan Mumusoglu, Gurkan Bozdag, Irem Yarali Ozbek, Peter Humaidan, Hakan YaraliABSTRACTResearch QuestionDoes intramuscular progesterone supplementation (imP4-suppl), secures ongoing pregnancy rates (OPRs) compared to vaginal progesterone-only (VP4) in hormone replacement therapy (HRT) cycles for frozen/thaw embryo transfer (FET); and moreover, is there a possible window of serum progesterone concentration out of which reproductive outcomes may be negatively impacted?DesignRetrospective longitudinal cohort stu...
Authors: Xiao X, Zhang J, Jin Y, Wang Y, Zhang Q Abstract Objective: To determine the effectiveness and safety of acupuncture for perimenopausal depression. Methods: We searched the Cochrane Central Register of Controlled Trials, PubMed, EMBASE, CNKI, VIP Citation Databases, Wan Fang, and online trial registries such as ClinicalTrials.gov for randomized controlled trials (RCTs) assessing the efficacy and safety of acupuncture for perimenopausal depression. Literature screening, data extraction, and determination of the risk of bias were performed by two researchers independently. The extracted data were pooled ...
We present a case of a 15-year-old adolescent girl with hypogonadism and coexisting medical conditions, who was evaluated for systemic hormone therapy. PMID: 32041392 [PubMed - in process]
This review focuses on the safety of hormone replacement therapy in women with a history of gynecologic cancer who have undergone surgery, chemotherapy, or radiation leading to early menopause.Menopause
There are many risk factors associated with breast cancer (BC) such as the familial history of BC, using hormone replacement therapy, obesity, personal habits, and other clinical factors; however, not all BC cases are attributed to these risk factors. Recent researches show a correlation between patient microbiome and BC suggested as a new risk factor. The present review article aimed at evaluating the role of the microbiome as a risk factor in the occurrence of BC, investigating the proposed mechanisms of interaction between the microbiome and human genes involved in BC, and assessing the impact of the altered composition...
Studies have suggested that hormones may play a potential role in melanoma carcinogenesis. Is hormone replacement therapy associated with an increased risk of melanoma in post-menopausal women?Human Reproduction
Commenting on recurring queries regarding shortages in hormone replacement therapy (HRT) medicines, Sandra Gidley, President of the Royal Pharmaceutical Society, said:‘There is a huge amount o
We present noninvasive imaging of estrogen receptors with 99mTc tamoxifen that can identify the active tumor and approachable sites for biopsy. It may help in selection of patients for hormone replacement therapy and in assessment of receptor status in recurrent disease and also in response evaluation.
We present a comprehensive review of acceptability, selected health outcomes above and HRT safety following risk reducing surgery.