The YrbE phospholipid transporter of Salmonella enterica serovar Typhi regulates the expression of flagellin and influences motility, adhesion and induction of epithelial inflammatory responses

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Source: Gut Microbes - Category: Microbiology Authors: Source Type: research

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In this study, we challenged three independent chick populations (Beijing You, Dwarf and Rhode Island Red) with SP at 4 days of age, and rectal temperature was measured before and after the SP attack from 2 to 7 days of age. Host defense to SP was evaluated by survival and spleen SP carrier status. The results showed that chicks with higher EBT before SP infection tend to have higher resistance to later SP attack in two populations (Dwarf and Beijing You). The association between EBT before SP attack and SP resistance was non-significant in Rohde Island Red population (P = 0.06), but the trend was consistent with the other...
Source: Frontiers in Genetics - Category: Genetics & Stem Cells Source Type: research
Scientists at the Federal University of Rio Grande do Sul in Brazil tested their theory on pisco sours cocktails and found the drink's alcohol and acidic lemon juice destroyed bacteria in nine minutes.
Source: the Mail online | Health - Category: Consumer Health News Source Type: news
ou Boué Each year in Europe, meat is associated with 2.3 million foodborne illnesses, with a high contribution from beef meat. Many of these illnesses are attributed to pathogenic bacterial contamination and inadequate operations leading to growth and/or insufficient inactivation occurring along the whole farm-to-fork chain. To ensure consumer health, decision-making processes in food safety rely on Quantitative Microbiological Risk Assessment (QMRA) with many applications in recent decades. The present study aims to conduct a critical analysis of beef QMRAs and to identify future challenges. A systematic app...
Source: International Journal of Environmental Research and Public Health - Category: Environmental Health Authors: Tags: Review Source Type: research
In primary infection with Salmonella, it has been reported—without consideration of Salmonella's functions—that humoral immunity plays no role in the clearance of bacteria. In fact, Salmonella targets and suppresses several aspects of humoral immunity, including B cell lymphopoiesis, B cell activation, and IgG production. In particular, the suppression of IgG-secreting plasma cell maintenance allows the persistence of Salmonella in tissues. Therefore, the critical role(s) of humoral immunity in the response to Salmonella infection, especially at the late phase, should be re-investigated. The suppression of IgG ...
Source: Frontiers in Immunology - Category: Allergy & Immunology Source Type: research
AbstractThe study evaluated the antibacterial activity of chlorogenic acid (CA) againstSalmonella Enteritidis  S1, a foodborne pathogen in chilled fresh chicken. Its minimum inhibitory concentration forS. Enteritidis  S1 was 2 mM. 1 MIC CA treatment reduced the viable count ofS. Enteritidis S1 by 3 log cfu/g in chilled fresh chicken. Scanning electron microscopy examination indicated that CA induced the cell envelope damage ofS. Enteritidis S1. Following this, 1-N-Phenylnaphthylamine assay and LPS content analysis indicated that CA induced the permeability of outer membrane (OM). Confocal laser scanning micr...
Source: World Journal of Microbiology and Biotechnology - Category: Microbiology Source Type: research
Conditions:   Ebola Virus Disease (Ebola Virus) & Differentials;   Malaria (Plasmodium Falciparum);   Typhoid Fever (Salmonella Typhi/Salmonella Parathyphi);   Dengue Fever (Dengue Virus);   Chikunkunya Fever (Chikunkunya Virus);   Yellow Fever (Yellow Fever Virus) Intervention:   Diagnostic Test: Differential RPA tests Sponsors:   University of Stirling;   Institut National de Recherche Biomédicale. Kinshasa, République Démocratique du Con...
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
(University of Gothenburg) A hitherto unknown antibiotic-resistant bacteria species, in the same family as E. coli and Salmonella spp., has been found and classified in Sweden. The proposed taxonomic name of the species -- the first of the new genus -- is Scandinavium goeteborgense, after the city of Gothenburg, Sweden, where the bacterium was isolated and the research was done.
Source: EurekAlert! - Infectious and Emerging Diseases - Category: Infectious Diseases Source Type: news
Contributors : Leon N Schulte ; Marco Metzger ; J örg VogelSeries Type : Expression profiling by high throughput sequencingOrganism : Homo sapiens ; Salmonella enterica subsp. enterica serovar Typhimurium str. SL1344Here, we introduce an intestinal tissue model to study human enteric infections. Our model comprises epithelial and endothelial layers, a primary intestinal collagen scaffold, and immune cells. We use Dual RNA-seq to chart the communication amongst several different cell types at the intestinal barrier and the pathogen. The results suggest that Salmonella uses its type III secretion systems to manipulate S...
Source: GEO: Gene Expression Omnibus - Category: Genetics & Stem Cells Tags: Expression profiling by high throughput sequencing Homo sapiens Salmonella enterica subsp. enterica serovar Typhimurium str. SL1344 Source Type: research
The objective of this study was to study the inactivation kinetics of Escherichia coli O157:H7 and Salmonella Typhimurium under microwave pasteurization at temperatures between 80 and 90 °C, i.e., at conditions that are employed in conventional pasteurization. Inoculated juices were treated at different power levels (600 W, 720 W) and treatment times (5s, 10s, 15s, 20s, 25s). Time-temperature profiles were obtained by fiber-optic sensors in contact with the samples allowing continuous data collection. The log-logistic and Arrhenius equations were used to account for the influence of the temperature histo...
Source: Food Microbiology - Category: Food Science Authors: Tags: Food Microbiol Source Type: research
This study evaluated Salmonella inactivation and cross-contamination in a simulated washing process of cherry and grape tomatoes. Commercially harvested tomatoes and the associated inedible plant matter (debris) were differentially inoculated with kanamycin resistant (KanR) or rifampin resistant (RifR) Salmonella strains, and washed together with uninoculated tomatoes in simulated packinghouse dump tank (flume) wash water. Washing in chlorinated water resulted in significantly higher Salmonella reduction on tomatoes than on debris, achieving 2-3 log reduction on tomatoes and about 1 log reduction on debris. Cross-contamina...
Source: Food Microbiology - Category: Food Science Authors: Tags: Food Microbiol Source Type: research
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