Proposition of a novel animal model of systemic sclerosis induced by type V collagen in C57BL/6 mice that reproduces fibrosis, vasculopathy and autoimmunity

Type V collagen (Col V) has the potential to become an autoantigen and has been associated with the pathogenesis of systemic sclerosis (SSc). We characterized serological, functional, and histopathological fea...

Source: Arthritis Research and Therapy - December 11, 2019 Category: Rheumatology Authors: Walcy Rosolia Teodoro, Zelita Aparecida de Jesus Queiroz, Lais Araujo dos Santos, Sergio Catanozi, Antonio dos Santos Filho, Cleonice Bueno, Margarete B. G. Vendramini, Sandra de Morais Fernezlian, Esmeralda M. Eher, Percival D. Sampaio-Barros, Sandra Gof Tags: Research article Source Type: research