Japanese partnership targets radiotherapeutics

Osaka University Graduate School of Medicine has signed a collaborative research...Read more on AuntMinnie.comRelated Reading: Isotope shows promise in brain cancer treatment New promise for therapeutic radiopharmaceuticals
Source: AuntMinnie.com Headlines - Category: Radiology Source Type: news

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The receptor deleted in colorectal cancer (DCC) and its ligand netrin-1 are essential for axon guidance during development and are expressed by neurons in the mature brain. Netrin-1 recruits GluA1-containing α...
Source: Molecular Brain - Category: Neuroscience Authors: Tags: Research Source Type: research
A pediatric brain cancer often caused by coincident mutations might be treated with a fungal analog.
Source: Signal Transduction Knowledge Environment - Category: Science Authors: Tags: STKE Editors ' Choice Source Type: news
Conditions:   Breast Cancer;   Brain Metastases Intervention:   Drug: Palbociclib, Trastuzumab, Lapatinib and Fulvestrant Sponsor:   wang shusen Not yet recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
ConclusionThe pre-SRS NLR, a systemic inflammatory marker for treatment response, inversely predicts local control, distant control and OS in patients with brain metastasis.
Source: Journal of Neuro-Oncology - Category: Cancer & Oncology Source Type: research
ConclusionIn MBM patients, complications after GKRS are not significantly increased if IT/TT treatment is performed at the time of or after radiosurgery. Further, a clear benefit in distant control and survival is seen in MBM patients treated with GKRS and checkpoint inhibitors. Thus, concomitant treatment of MBM with GKRS and IT/TT seems to be a safe and powerful treatment option although further prospective studies should be conducted.
Source: Cancer Medicine - Category: Cancer & Oncology Authors: Tags: ORIGINAL RESEARCH Source Type: research
This study delves into the mechanisms by which a short period of fasting can accelerate wound healing. Fasting triggers many of the same cellular stress responses, such as upregulated autophagy, as occur during the practice of calorie restriction. It isn't exactly the same, however, so it is always worth asking whether any specific biochemistry observed in either case does in fact occur in both situations. In particular, the period of refeeding following fasting appears to have beneficial effects that are distinct from those that occur while food is restricted. Multiple forms of therapeutic fasting have been repor...
Source: Fight Aging! - Category: Research Authors: Tags: Newsletters Source Type: blogs
CONCLUSIONS: Neurological involvement in MM encompasses a myriad of variants and while the clinical setting varies from one patient to another, an underlining neoplasia should be evaluated in suspected patients. PMID: 32239096 [PubMed - in process]
Source: Romanian Journal of Morphology and Embryology - Category: General Medicine Tags: Rom J Morphol Embryol Source Type: research
AbstractCancer-associated thrombosis is known as Trousseau syndrome (TS). Here, we report 4 cases of TS associated with advanced breast cancer that caused central nervous system (CNS) vascular events. All 4 patients experienced sudden onset of CNS symptoms. Imaging revealed multiple brain infarctions or intracranial hemorrhage and all 4 patients had leptomeningeal or brain metastasis. Laboratory findings showed hypercoagulability at diagnosis of TS. Of the 4 patients, 2 patients were treated with unfractionated heparin, while 2 patients could not undergo anticoagulant therapy. In all patients, once the TS occurred, the CNS...
Source: International Cancer Conference Journal - Category: Cancer & Oncology Source Type: research
One of the biggest challenges of this unsettling time is the isolation we feel as we’re separated from friends and family, all the people for whom we care most deeply. But just being alone is only part of the difficulty. Our sense of remoteness is intensified by a pall of unease we can’t define: Loss and sorrow are also in the air. We fear losing—or we may have already lost—people we love. And when we work up the courage to look beyond our individual personal spheres, we see that many people who have made our world better, in big and small ways, have vanished before we were ready to let them go. But...
Source: TIME: Health - Category: Consumer Health News Authors: Tags: Uncategorized COVID-19 feature remembrance Source Type: news
Conditions:   Gut Microbiota;   NSCLC;   Pembrolizumab;   Chemotherapy Intervention:   Drug: Pembrolizumab Combined With Chemotherapy Sponsor:   Xiaorong Dong Not yet recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
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