Distribution of insecticide resistance and mechanisms involved in the arbovirus vector < i > Aedes aegypti < /i > in Laos and implication for vector control

ConclusionsThese results suggest that bothkdr mutations and metabolic resistance mechanisms are present in Laos but their impact on phenotypic resistance may differ in proportion at the population or individual level. Molecular analyses suggest that CNV affectingCCEAE3A previously associated with temephos resistance is also associated with malathion resistance while CNV affectingCYP6BB2 andCYP6P12 are associated with pyrethroid and possibly DDT resistance. The presence of high levels of insecticide resistance in the main arbovirus vector in Laos is worrying and may have important implications for dengue vector control in the country.
Source: PLoS Neglected Tropical Diseases - Category: Tropical Medicine Authors: Source Type: research