IJERPH, Vol. 16, Pages 5071: Acute Limb Ischemia after Intake of the Phenylethylamine Derivate NBOMe

Conclusion: NBOMe ingestion implicates the risk of peripheral vasospasms with severe, limb-threatening ischemia.
Source: International Journal of Environmental Research and Public Health - Category: Environmental Health Authors: Tags: Brief Report Source Type: research

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Publication date: Available online 25 January 2020Source: The American Journal of SurgeryAuthor(s): Mitchell G. Bryski, Lydia G. Frenzel-Sulyok, Lewis Kaplan, Sunil Singhal, Jane J. KeatingAbstractAcute mesenteric ischemia (AMI) is a deadly and common surgical emergency. While several imaging modalities aid in the diagnosis of AMI preoperatively, there are limited intraoperative tools for surgeon decision making regarding bowel viability. Here we offer a review of the utility and limitations of the many extensively studied techniques. We classify each of these modalities into three hallmarks of healthy bowel: oxygenation, ...
Source: The American Journal of Surgery - Category: Surgery Source Type: research
ConclusionsThis is the largest series to date reporting>30-day follow-up for patients undergoing venous ablation procedures while receiving anticoagulation and the longest follow-up reported of any series. Durability, safety, and efficacy of vein ablation in patients receiving anticoagulation are comparable to those in control patients. Anticoagulation should not be considered a contraindication to endothermal ablation of the GSV or SSV for symptomatic venous reflux.
Source: Journal of Vascular Surgery: Venous and Lymphatic Disorders - Category: Surgery Source Type: research
Publication date: Available online 24 January 2020Source: Sensing and Bio-Sensing ResearchAuthor(s): R. Shekarriz, D.M. Friedrichsen, B. Brooks, G. Silaski, L. Rios, E. Wiest, N.L. KanagyAbstractA nanoporous gold electrocatalytic technique has been reported for detection of gas-phase hydrogen sulfide (H2S) molecules at trace levels relevant to physiological measurements. H2S is a known biomarker generated within the walls of arteries and can be linked to peripheral artery disease (PAD) and small vessel disease (SVD). The detection technique presented herein demonstrates suitability of transdermal monitoring of H2S linked t...
Source: Sensing and Bio Sensing Research - Category: Research Source Type: research
Publication date: Available online 24 January 2020Source: Journal of Vascular and Interventional RadiologyAuthor(s): Yumei Yang, Yanfang Zhang, Yumin Wu, Jibing Chen, Bing Liang, Quanhong Chen, Qiuyu Wang, Jialing Lyu, Yong Li, Feng Mu, Duanming DuAbstractPurposeTo evaluate the efficacy and safety of percutaneous argon-helium cryoablation (CA) for hepatocellular carcinoma (HCC) abutting the diaphragm (
Source: Journal of Vascular and Interventional Radiology - Category: Radiology Source Type: research
Conclusion: Some patients with psychiatric syndromes and increased ANA titers may suffer from psychiatric variants of SLE, even if the American College of Rheumatology criteria for SLE are not met. Whether the psychiatric symptoms in our patient represent a prodromal stage with the later manifestation of full-blown SLE or a subtype of SLE with isolated CNS involvement remains unclear. Regardless, early diagnosis and initiation of immunosuppressive treatment are essential steps in preventing further disease progression and organ damage. Intrathecal ANAs with extractable nuclear antigen differentiation may be a more sensitiv...
Source: Frontiers in Psychiatry - Category: Psychiatry Source Type: research
Purpose of review To examine the recent literature regarding sudden death in patients with schizophrenia and synthesize salient conclusions based on this evidence. Recent findings Sudden cardiac death (SCD) is the largest subset of sudden unexpected death (SUD), with up to 40% of SUD from cardiovascular causes. SCD has been associated with exposure to both first and second-generation antipsychotics. Clozapine [odds ratio (OR) 3.67, 95% confidence interval (CI) 1.94–6.94] confers the highest risk of SCD followed by risperidone (OR 3.04, 95% CI 2.39–3.86) then olanzapine (OR 2.04, 95% CI 1.52–2.74). SC...
Source: Current Opinion in Psychiatry - Category: Psychiatry Tags: SCHIZOPHRENIA AND RELATED DISORDERS: Edited by Lynn E. DeLisi and Iris E. Sommer Source Type: research
The goal of this manuscript is to explain how stress is critically involved in the pathophysiology of a cluster of uniquely human diseases which include migraine headaches, hypertension, metabolic syndrome (obesity), stroke, deep vein thrombosis (DVT)/pulmonary emboli (PE), auto-immune diseases, schizophrenia, post-traumatic stress disorder, Alzheimer ’s disease, and atherosclerosis. As is familiar to clinicians, some people have several of these diagnoses while other people are apparently healthy and have not a single one—the diseases tend to come as a “package deal”.
Source: Medical Hypotheses - Category: Biomedical Science Authors: Tags: Editorial$Author's introduction Source Type: research
Conclusion In closing, our patient’s episode of TGA combined with her emotional and perceptual response lends credence to the proposal of a “fear/paranoia” circuit in the genesis of paranoid delusions—a circuit incorporating amygdala, frontal, and parietal cortices. Here, neutral or irrelevant stimuli, thoughts, and percepts come to engender fear and anxiety, while dysfunction in frontoparietal circuitry engenders inappropriate social predictions and maladaptive inferences about the intentions of others.[54] Hippocampus relays information about contextual information based on past experiences and th...
Source: Innovations in Clinical Neuroscience - Category: Neuroscience Authors: Tags: Anxiety Disorders Behavioral and Cognitive Neurology Case Report Cognition Current Issue Dementia Medical Issues Neurologic Systems and Symptoms Psychiatry Schizophrenia delusions hippocampus neurobiology Transient global amnesia Source Type: research
The approval of first-of-a-kind drugs rose last year to forty-one, resulting in the highest level of newly approved U.S. drugs in nineteen years. The total number of new drugs approved last year was even higher at sixty-nine. The rising figures reflect an industry-wide desire to research and develop drugs for rare and hard-to-treat diseases. The newly approved drugs serve to advance medical care and the health of patients suffering from many ailments, including various forms of cancer, heart failure, and cystic fibrosis. Additionally, more than 40% of the new therapies were approved for treatment of rare or "orphan&...
Source: Policy and Medicine - Category: American Health Authors: Source Type: blogs
Commentary on: Vigod SN, Kurdyak PA, Dennis CL, et al.. Maternal and newborn outcomes among women with schizophrenia: a retrospective population-based cohort study. BJOG 2014;121:566–74. Implications for practice and research Higher rates of preterm delivery and small for gestational age (SGA) babies in schizophrenic mothers confirm previous findings in the context of newer antipsychotic drugs and treatment practices. Women with schizophrenia should be counselled about increased risks and followed by a provider specialising in high-risk pregnancies. Strategies to address modifiable risk factors during pregnancy and t...
Source: Evidence-Based Nursing - Category: Nursing Authors: Tags: Midwifery, Hypertension, Pregnancy, Reproductive medicine, Child and adolescent psychiatry (paedatrics), Child health, Infant health, Neonatal health, Venous thromboembolism, Child and adolescent psychiatry, Drugs: psychiatry, Psychotic disorders (incl sc Source Type: research
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