Abnormal paravertebral muscles development is associated with abnormal expression of PAX3 in adolescent idiopathic scoliosis

ConclusionThePAX3 muscle expression and paravertebral muscle volume were asymmetric in AIS patients, and the expression ratio was positively related with the muscle volume ratio. These findings suggestedPAX3 might have functional role in the development of AIS via regulating development of paravertebral muscle.Graphic abstractThese slides can be retrieved under Electronic Supplementary Material.

http://link.springer.com/10.1007/s00586-019-06217-5

Source: European Spine Journal - December 11, 2019 Category: Orthopaedics Source Type: research