Autoimmune musicogenic epilepsy associated with anti ‐glutamic acid decarboxylase antibodies and Stiff‐person syndrome

Epilepsy should be suspected in patients with Stiff ‐person syndrome and new onset paroxysmal episodes. Musicogenic epilepsy may be a manifestation of anti‐GAD‐Ab spectrum, supporting an autoimmune workup in these patients. Appropriate treatment is not well established, and immunotherapy should be considered in patients with only partial respon se to antiepileptic drugs. AbstractEpilepsy should be suspected in patients with Stiff ‐person syndrome and new onset paroxysmal episodes. Musicogenic epilepsy may be a manifestation of anti‐GAD‐Ab spectrum, supporting an autoimmune workup in these patients. Appropriate treatment is not well established, and immunotherapy should be considered in patients with only partial respon se to antiepileptic drugs.

Source: Clinical Case Reports - December 11, 2019 Category: General Medicine Authors: Joana Jesus ‐Ribeiro, Alireza Bozorgi, Modhi Alkhaldi, Mahmoud Shaqfeh, Guadalupe Fernandez‐Baca Vaca, Bashar Katirji Tags: CASE REPORT Source Type: research