Temporal pattern of tuberculosis cure, mortality, and treatment abandonment in Brazilian capitals.

CONCLUSION: the rates of cure and abandonment are far from the ones recommended by the World Health Organization, showing that Brazilian capitals need interventions aimed at changing this pattern. PMID: 31826160 [PubMed - in process]
Source: Revista Latino-Americana de Enfermagem - Category: Nursing Authors: Tags: Rev Lat Am Enfermagem Source Type: research

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Publication date: Available online 21 January 2020Source: Preventive Veterinary MedicineAuthor(s): Laetitia Canini, Benoit DurandAbstractFrance was recognized officially bovine tuberculosis (bTB) free by the European Union in 2001, however an increase of bTB detections has been reported since 2004. Even though the recommended method for bTB control is whole herd depopulation, test-and-cull protocols have been authorized in pilot areas since 2008 and in the rest of France since 2014. BTB impact at the state level and on trade has been thoroughly studied, however the consequences of these control measures at a farm level are...
Source: Preventive Veterinary Medicine - Category: Veterinary Research Source Type: research
In this study, specific primers and MGB probes were designed according to the mutation in PstS1 gene, and a sensitive, specific and rapid real-time PCR assay for M. bovis was established. Then the assay was used to detect M. bovis in simulation samples. The minimum detectable concentration is 101 copies for M. bovis DNA. The standard curve showed correlation coefficient between threshold cycle and PstS1 gene fragment copy number was 0.997 and slope is −3.144. The minimum detectable concentration is 101 cells/ml for simulation sample. In addition, M.bovis strain 93006, 14 clinical BCG stains and 7 clinical M.bovi...
Source: Biologicals - Category: Biology Source Type: research
ConclusionsTB can have varied presentation and therefore it is essential to keep tubercular infection in differential diagnosis while working up for any infective pathology. Conservative treatment produces good results in vast majority of cases. Surgery is reserved for select indications.
Source: Journal of Clinical Orthopaedics and Trauma - Category: Orthopaedics Source Type: research
A deep-learning algorithm that analyzed chest x-rays was able to predict pulmonary...Read more on AuntMinnie.comRelated Reading: Deep-learning algorithm bolsters lung cancer detection AI may help improve sensitivity of ED chest x-ray reads AI model could speed up pneumonia diagnosis in ED AI detects pulmonary nodules on chest x-rays Are studies on AI for tuberculosis really valid?
Source: AuntMinnie.com Headlines - Category: Radiology Source Type: news
Publication date: Available online 21 January 2020Source: Microbial PathogenesisAuthor(s): Guoying Deng, Na Ji, Xiaoxia Shi, Wenli Zhang, Yuanhua Qin, Shanshan Sha, Shufeng Yang, Yufang MaAbstractMycobacterium tuberculosis is capable of escaping the clearance of immune system mainly due to its complex constituents of cell wall. Certain studies show that glycoproteins are involved in immune evasion and act as virulence factors. Peptidoglycan deacetylase Rv1096 is a member of mannosylated proteins. Previously, we reported Rv1096 protein contributed to the resistance of Mycobacterium smegmatis (M. smegmatis) to lysozyme, but ...
Source: Microbial Pathogenesis - Category: Infectious Diseases Source Type: research
Condition:   Tuberculosis Infection Intervention:   Other: TB infection-screening benefiting group Sponsors:   Hospital Mutua de Terrassa;   Public Health Agency of Barcelona;   Hospital Vall d'Hebron;   Hospital Sant Joan de Deu;   Institut Català de la Salut;   Hospital Universitari Sant Joan de Reus;   Hospital de Tortosa Verge de la Cinta Recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
Conditions:   Pulmonary Tuberculosis;   Extra Pulmonary Tuberculosis Intervention:   Genetic: immunogenetics Sponsor:   Assistance Publique - Hôpitaux de Paris Recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
This study evaluated the HIV/TB co-infection rate among HIV-1 infected individuals in old Cross River State, Nigeria. A total of 417 HIV-infected individuals participated in this study, 241 (57.8%) from Calabar, Cross River State, Nigeria and 176 (42.2%) from Uyo, Akwa-Ibom State, Nigeria. The age range of the 417 HIV-1 positive individuals who participated in the study was 4-72 years with an average age of 39.1 years. Plasma samples were analyzed for HIV and TB using fourth-generation Enzyme-Linked immunosorbent Assay. The CD4 count was enumerated using the Partec CyFlow® Counter. Plasma viral loads (PVL) we...
Source: Journal of Immunoassay and Immunochemistry - Category: Biochemistry Tags: J Immunoassay Immunochem Source Type: research
[East African] The Global Fund, the body that finances the world's HIV, tuberculosis (TB) and malaria programmes, has given Kenya Ksh42 billion ($420 million) to cover the intervening years to 2024.
Source: AllAfrica News: Health and Medicine - Category: African Health Source Type: news
Publication date: Available online 20 January 2020Source: International Journal of PaleopathologyAuthor(s): Elizabeth A. Nelson, Jane E. Buikstra, Alexander Herbig, Tiffiny A. Tung, Kirsten I. BosAbstractAndean paleopathological research has significantly enhanced knowledge about the geographical distribution and evolution of tuberculosis (TB) in pre-Columbian South America. In this paper, we review the history and progress of research on ancient tuberculosis (TB) in the Andean region, focusing on the strengths and limitations of current approaches for the molecular detection of ancient pathogens, with special attention to...
Source: International Journal of Paleopathology - Category: Pathology Source Type: research
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