A complicated pregnancy in homozygous familial hypercholesterolaemia treated with lipoprotein apheresis: A case report.

CONCLUSIONS: LA is a safe and effective tool in HoFH subjects even in pregnancy. Evidence based guidelines for the management of these patients during pregnancy are still lacking. PMID: 31818440 [PubMed - in process]
Source: Atherosclerosis Supplements - Category: Cardiology Authors: Tags: Atheroscler Suppl Source Type: research

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Publication date: Available online 15 January 2020Source: Neuroscience &Biobehavioral ReviewsAuthor(s): Anna Xu, Bart Larsen, Erica B. Baller, J. Cobb Scott, Vaishnavi Sharma, Azeez Adebimpe, Allan I. Basbaum, Robert H. Dworkin, Robert R. Edwards, Clifford J. Woolf, Simon B. Eickhoff, Claudia R. Eickhoff, Theodore D. SatterthwaiteAbstractCharacterizing a reliable, pain-related neural signature is critical for translational applications. Many prior fMRI studies have examined acute nociceptive pain-related brain activation in healthy participants. However, synthesizing these data to identify convergent patterns of activa...
Source: Neuroscience and Biobehavioral Reviews - Category: Neuroscience Source Type: research
Authors: Fontes MAP, Marzano LAS, Silva CC, Silva ACSE Abstract Despite the current availability of safe and efficient drugs for treating hypertension, a substantial number of patients are drug-resistant hypertensives. Aiming this condition, a relatively new approach named catheter-based renal denervation was developed. We have now a clinically relevant time window to review the efficacy of renal denervation for treating this form of hypertension. This short review addresses the physiological contribution of renal sympathetic nerves for blood pressure control and discusses the pros and cons of renal denervation pro...
Source: Jornal Brasileiro de Nefrologia - Category: Urology & Nephrology Tags: J Bras Nefrol Source Type: research
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Source: Journal of Agromedicine - Category: Environmental Health Authors: Source Type: research
Link N suppresses interleukin-1β-induced biological effects on human osteoarthritic cartilage. Eur Cell Mater. 2020 Jan 15;39:65-76 Authors: Alaqeel M, Grant MP, Epure LM, Salem O, AlShaer A, Huk OL, Bergeron SG, Zukor DJ, Kc R, Im HJ, Anbazhagan AN, Antoniou J, Mwale F Abstract Osteoarthritis (OA) is a disease of diarthrodial joints associated with extracellular matrix proteolytic degradation under inflammatory conditions, pain and disability. Currently, there is no therapy to prevent, reverse or modulate the disease course. The present study aimed at evaluating the regenerative potential of Link...
Source: European Cells and Materials - Category: Cytology Tags: Eur Cell Mater Source Type: research
In conclusion, implementation of the CMD prevention program resulted in the detection of two- to threefold more patients with CMD. A significant drop in systolic blood pressure and cholesterol levels was found after one year of treatment. Modelling of these results should confirm the effect on long term endpoints.Trial registration: Dutch trial Register number NTR4277.
Source: Preventive Medicine - Category: International Medicine & Public Health Source Type: research
Publication date: Available online 15 January 2020Source: Preventive MedicineAuthor(s): Kathleen Gali, Ruth Narode, Kelly C. Young-Wolff, Mark L. Rubinstein, Geoffrey Rutledge, Judith J. ProchaskaAbstractCannabis has been legalized, decriminalized, or medicalized in over half the U.S. states. With restrictions on cannabis research, accepted standards to guide clinical practice are lacking. Analyzing online communications through a digital health platform, we characterized patient questions about cannabis use and provider responses. Coded for content were 4579 questions posted anonymously online between March 2011 through J...
Source: Preventive Medicine - Category: International Medicine & Public Health Source Type: research
Want to ask people's opinion on this. Has been a follower on this forum and have found the input and discussion valuable Recently I have a few patients came to me, some by referral, but they don't have insurance, they want to pay cash for their visits but only want me to manage their opioid. Sometime I just don't know what to do with these patients, if I recommend procedures, it's probably too costly and they won't be able to afford or no interest in pursuing. I just don't like the optic of... Cash pay for narcotics
Source: Student Doctor Network - Category: Universities & Medical Training Authors: Tags: Pain Medicine Source Type: forums
In conclusion, in the absence of obesity, visceral adipose tissue possesses a pronounced anti-inflammatory phenotype during aging which is further enhanced by exercise. Methods of Inducing Cellular Damage are Rarely Relevant to Aging, and the Details Matter https://www.fightaging.org/archives/2019/08/methods-of-inducing-cellular-damage-are-rarely-relevant-to-aging-and-the-details-matter/ One of the major challenges in aging research is determining whether or not models of cellular or organismal damage and its consequences are in any way relevant to the natural processes of aging. One can hit a brick with...
Source: Fight Aging! - Category: Research Authors: Tags: Newsletters Source Type: blogs
Lilly Rocha was 37 years old in 2008 when she began having strange symptoms. When people asked her questions, she knew the answers but couldn’t articulate them. A tingling sensation on her left breast became painful. She thought she might have breast cancer, but her doctor assured her she was just experiencing stress from her demanding job. Her symptoms continued to get worse, and doctors continued to dismiss her. Three months later, at work, she became seriously ill. Luckily, her boss recognized the symptoms—chest and jaw pain and numbness in her left hand—and drove her to the nearest emergency room, whe...
Source: TIME: Health - Category: Consumer Health News Authors: Tags: Uncategorized heart health Source Type: news
Is the pain heartburn or a heart attack? How can you tell the difference between a sharp, burning sensation in your chest caused by the pizza you just ate or a sign of something more serious? Women’s heart attack symptoms can be difficult to diagnose. My heart attack absolutely started out feeling like heart burn. I’ve experienced both severe heartburn and a heart attack and the pain is very similar at the beginning. Here are 7 ways to tell the difference between heartburn and a heart attack: Did you just eat something which upset your stomach? If your tummy is usually upset 30 to 40 minutes after eating spicy...
Source: Embrace Your Heart Wellness Initiative - Category: Cardiology Authors: Tags: Award Winning Blog Heart Health Source Type: blogs
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