Renal Scarring is the Most Significant Predictor of Breakthrough Febrile Urinary Tract Infection in Patients with Simplex and Duplex Primary Vesico-Ureteral Reflux

The association of high-grade vesico-ureteral reflux (VUR) with renal dysplasia and/or scarring is well-established, and the combination of these factors has been shown to decrease the likelihood of VUR resolution. Other VUR parameters have similarly been shown to be associated with VUR non-resolution, including VUR grade and timing at cystography, associated urinary tract anatomical abnormalities, and bladder dysfunction.

Source: Journal of Pediatric Urology - December 10, 2019 Category: Urology & Nephrology Authors: Stavros P. Loukogeorgakis, Katherine Burnand, Alex MacDonald, Katherine Wessely, Diane De Caluwe ’, Nisha Rahman, Marie-Klaire Farrugia Source Type: research