T-2 toxin impairs antifungal activities of chicken macrophages against Aspergillus fumigatus conidia but promotes the pro-inflammatory responses.

In conclusion, T-2 impaired the antifungal activities of chicken macrophages against A. fumigatus conidia, but might stimulate immune response by upregulating the expression of pro-inflammatory cytokines, chemokines and T-helper 1 cytokines.
PMID: 23930935 [PubMed - as supplied by publisher]

Source: Avian Pathology - August 9, 2013 Category: Pathology Authors: Li SJ, Pasmans F, Croubels S, Verbrugghe E, Van Waeyenberghe L, Yang Z, Haesebrouck F, Martel A Tags: Avian Pathol Source Type: research