Stable carbon isotope analysis of polyphosphonate complexing agents by anion chromatography coupled to isotope ratio mass spectrometry: method development and application.

Stable carbon isotope analysis of polyphosphonate complexing agents by anion chromatography coupled to isotope ratio mass spectrometry: method development and application. Anal Bioanal Chem. 2019 Dec 07;: Authors: Martin PR, Buchner D, Jochmann MA, Haderlein SB Abstract Compound-specific carbon isotope analysis (carbon CSIA) by liquid chromatography/isotope ratio mass spectrometry (LC-IRMS) is a novel and promising tool to elucidate the environmental fate of polar organic compounds such as polyphosphonates, strong complexing agents for di- and trivalent cations with growing commercial importance over the last decades. Here, we present a LC-IRMS method for the three widely used polyphosphonates 1-hydroxyethane 1,1-diphosphonate (HEDP), amino tris(methylenephosphonate) (ATMP), and ethylenediamine tetra(methylenephosphonate) (EDTMP). Separation of the analytes, as well as ATMP and its degradation products, was carried out on an anion exchange column under acidic conditions. Quantitative wet chemical oxidation inside the LC-IRMS interface to CO2 was achieved for all three investigated polyphosphonates at a comparatively low sodium persulfate concentration despite the described resilience of HEDP towards oxidative breakdown. The developed method has proven to be suitable for the determination of carbon isotope fractionation of ATMP transformation due to manganese-catalyzed reaction with molecular oxygen, as well as for equilibrium sorptio...
Source: Analytical and Bioanalytical Chemistry - Category: Chemistry Authors: Tags: Anal Bioanal Chem Source Type: research