Angiomyomatous hamartoma in the inguinal lymph node: A case report and literature review

We present a case of a 57-year-old white female with a left upper thigh mass located at the previous surgical site of the resection of a 15 cm, 505-glipoma 10 years ago. Magnetic resonance imaging showed a 1.7 × 3.1 × 2.9 cm soft tissue mass within the subcutaneous adipose tissues of her left upper thigh at the site of previous lipoma resection. No muscle or bone invasion was identified. The clinical impression was lipoma versus liposarcoma. The mass was surgically removed, and gross examination showed a tan-pink, well-demarcated soft mass with scalloped edges noted within the yellowish adipose tissue. The histologic sections revealed several lymph nodes with parenchymal replacement by smooth muscle bundles, adipose tissue, and blood vessels with a fibrous stroma. Caldesmon and desmin highlighted the muscular component. CD34 and CD31 stained the vascular endothelium. To our best knowledge, this is the first case of angiomyomatous hamartoma at the site of a previously resected lipoma. This unexpected finding adds an unusual differential diagnosis along with the far more common recurrent soft tissue tumor.
Source: Human Pathology: Case Reports - Category: Pathology Source Type: research