Renal Effects after Pembrolizumab Treatment for Non-small Cell Lung Carcinoma: A Case Report.

In this report, we focus on the correct diagnosis and management of renal irAEs, which remain controversial. PMID: 31813918 [PubMed - as supplied by publisher]
Source: Internal Medicine - Category: Internal Medicine Tags: Intern Med Source Type: research

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Publication date: April 2020Source: Biomedicine &Pharmacotherapy, Volume 124Author(s): Zhiguang Yang, Xingyu Lin, Peng Zhang, Yunpeng Liu, Zihao Liu, Benxin Qian, Xing Liu, Guoguang ShaoAbstractLong non-coding RNA LINC00525 has been reported to be upregulated in non-small cell lung cancer (NSCLC), however, its biological roles and underlying mechanism involved in modulation of NSCLC remain largely unclear. Real-time PCR were performed to determine the expression of LINC00525 and miR-338-3p in NSCLC tissues and cell lines. Cell proliferation was detected by Cell Counting Kit-8 (CCK-8) and colony-formation assays. Cell m...
Source: Biomedicine and Pharmacotherapy - Category: Drugs & Pharmacology Source Type: research
Authors: Tan NP, Majeed A, Roberts SK, Gow PJ, Hey P, Mah X, Goodwin M, Sood S, Lubel J, Nicoll A, Dev A, Bell SJ, Kemp WW PMID: 31981417 [PubMed - as supplied by publisher]
Source: Medical Journal of Australia - Category: General Medicine Tags: Med J Aust Source Type: research
Publication date: March–April 2020Source: Reports of Practical Oncology &Radiotherapy, Volume 25, Issue 2Author(s): Ramaiah Vinay Kumar, Suman BhaskerAbstractObesity has become epidemic both in developed and developing countries. Socio-economic (SE) development has resulted in increased prevalence of obesity across all social groups in developing countries that is contrary to the effects of rising SE status on prevalence of obesity in the developed world. Obesity is not only associated with metabolic syndrome, cardiovascular disease, diabetes but is also a risk factor for cancer and is responsible for increased c...
Source: Reports of Practical Oncology and Radiotherapy - Category: Cancer & Oncology Source Type: research
Conclusion: EBRT can yield favorable local control in HCC with IVC and/or RA involvement. Systemic treatment may be more indicated as factors reflecting tumor aggressiveness were significant, and first distant failure is common. PMID: 31977276 [PubMed - as supplied by publisher]
Source: International Journal of Radiation Biology - Category: Radiology Tags: Int J Radiat Biol Source Type: research
Conclusions. Today biological specimens donated by 343 registrants with lung cancer are available at the RHTR. Among them, 255 donors (74%) are Mayak PA workers hired at the main facilities (reactors, plutonium production and radiochemical plants) in 1948-1982. These workers donated about 6024 specimens of lung tissues (tumor and tumor-free) stored mostly as formalin-fixed paraffin-embedded tissue blocks (31%) and histology slides (64%); in addition they donated 1800 specimens of blood/blood components, buccal epithelium cells and sputum. Among histologic types identified for these lung cancer cases, adenocarcinoma and sma...
Source: International Journal of Radiation Biology - Category: Radiology Tags: Int J Radiat Biol Source Type: research
Publication date: Available online 22 January 2020Source: Sensors and Actuators B: ChemicalAuthor(s): Mingyu Cheng, Fan Zhang, Aonan Zhu, Xiaolong Zhang, Yaxin Wang, Xiaoyu Zhao, Lei Chen, Zhong Hua, Yongjun Zhang, Xuefeng ZhangAbstractDetecting biomarkers with high sensitivity is key for the early diagnosis of hepatocellular carcinoma (HCC). Nanostructure units with knobby surface are bridged to obtain significant surface-enhanced Raman scattering (SERS) signals. This changes the plasma coupling mode and the hotspots distribution between neighboring units as confirmed by finite-difference time-domain simulations. These ar...
Source: Sensors and Actuators B: Chemical - Category: Chemistry Source Type: research
Publication date: Available online 25 January 2020Source: Journal of Photochemistry and Photobiology B: BiologyAuthor(s): Mosar Corrêa Rodrigues, Lívia Gumieri Vieira, Frederíco Hillesheim Horst, Eduarda Campos de Araújo, Rayane Ganassin, Carolin Merker, Thomas Meyer, Julia Böttner, Tom Venus, João Paulo F. Longo, Sacha Braun Chaves, Mônica Pereira Garcia, Irina Estrela-Lopis, Ricardo Bentes Azevedo, Luis Alexandre MuehlmannAbstractPhotodynamic therapy (PDT) is effective in the treatment of different types of cancer, such as basal cell carcinoma and other superficial cancers. Ho...
Source: Journal of Photochemistry and Photobiology B: Biology - Category: Speech-Language Pathology Source Type: research
CONCLUSION: Mammography was more accurate than ultrasonography in measuring the largest cancer diameter in DCIS of breast cancer. The correlation coefficient improved in the group of almost entirely fatty/ scattered areas of fibroglandular dense breast or in microcalcification negative group. PMID: 31975667 [PubMed - in process]
Source: Current Medical Imaging Reviews - Category: Radiology Tags: Curr Med Imaging Rev Source Type: research
CONCLUSION: This paper aims to serve as a foundation guidance for the reader to attain bird's eye understanding on breast carcinoma disease and its current non-invasive modalities. PMID: 31975658 [PubMed - in process]
Source: Current Medical Imaging Reviews - Category: Radiology Tags: Curr Med Imaging Rev Source Type: research
Conclusions: The results reveal high discriminant power of chromosomes 8, 5, 1, 3, and 19 for identifying cancer with the highest sensitivity of 75% yielded by chromosome 5. Bottom 5 chromosomes 9, 6, 4, 13, and 21 show low discriminant power with accuracy of below 54% where true cancer and normal samples are grouped into substantially overlapping groups using copy numbers. This indicates the similarities of copy numbers obtained for cancer and normal samples on these chromosomes. PMID: 31977287 [PubMed - as supplied by publisher]
Source: Cancer Investigation - Category: Cancer & Oncology Tags: Cancer Invest Source Type: research
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